Publications by authors named "Silvia Fernandez Garcia"

Objective: To characterise patients with heart failure (HF) in Primary Health Care (PHC) and describe their socio-demographic and clinical characteristics and pharmacological treatment.

Design: Descriptive cohort study. SITE: Information System for the Development of Research in Primary Care (SIDIAP), which captures information from the electronic health records of PHC of the Catalan Institute of Health (approximately 80% of the Catalan population).

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Objective: Studies evaluating urine culture requests in our country have highlighted a high rate of requests that fall outside the indications specified in clinical guidelines. We evaluated the current degree of inadequacy in the request of urine cultures and how this influences the therapeutic decisions of general practitioners.

Design: Cross-sectional descriptive study.

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Objective: Central diabetes insipidus or vasopressin deficiency (AVP-D) is the most frequent water balance disorder after transsphenoidal surgery (TSS) with variable prevalence amongst studies. We aimed to determine rates of newly developed transient or permanent AVP-D in patients with pituitary tumours treated with TSS.

Design And Methods: We performed systematic review of Medline, Embase, and Cochrane Library between January 1, 2000 and January 31, 2021 for studies reporting on outcomes for pituitary adenoma, craniopharyngioma, and Rathke's cleft cyst (RCC) after TSS and providing definition of post-operative AVP-D.

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Objective: To assess the effects of COVID-19 vaccines in women before or during pregnancy on SARS-CoV-2 infection-related, pregnancy, offspring and reactogenicity outcomes.

Design: Systematic review and meta-analysis.

Data Sources: Major databases between December 2019 and January 2023.

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Article Synopsis
  • The study investigates the risks of complications associated with twin pregnancies conceived through Assisted Reproductive Technology (ART) compared to those conceived naturally or through non-ART methods.
  • It systematically reviews maternal and perinatal outcomes using data from 111 studies, focusing solely on twin pregnancies to avoid discrepancies from including higher order multiples like triplets.
  • Findings show that ART-conceived twins are at a significantly higher risk for issues like preterm birth, hypertensive disorders, gestational diabetes, and requiring cesarean deliveries compared to non-ART twins, with notable statistical evidence supporting these risks.
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Antimicrobial resistance is a major global problem that is primarily driven by the excessive and inappropriate utilization of antibiotics. Urinary tract infections (UTIs) are frequent in primary health care (PHC) and are typically treated with antibiotics. There is ample evidence on the management of this condition in women but not in men.

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Background: Alopecia areata is an autoimmune disease leading to nonscarring hair loss on the scalp or body. There are different treatments including immunosuppressants, hair growth stimulants, and contact immunotherapy.

Objectives: To assess the benefits and harms of the treatments for alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) in children and adults.

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Article Synopsis
  • - The study investigates the effectiveness of four biomarkers (procalcitonin, C-reactive protein, interleukin-6, and presepsin) in predicting mortality in critically ill adults with sepsis, addressing inconsistencies found in previous research.
  • - A systematic review and meta-analysis of 60 studies involving over 15,000 patients revealed a high risk of bias in more than 60% of assessments for these biomarkers as prognostic indicators.
  • - The findings indicate that baseline measurements of these biomarkers do not reliably predict mortality outcomes, suggesting that their role in sepsis prognosis may be limited.
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Background: Antibiotic resistance is an individual and public health problem; multidrug-resistant infections could cause an estimated 10 million deaths worldwide by 2050. Unnecessary use of antimicrobials is the most important cause of resistance generation in the community, and an estimated 80% of antimicrobials are prescribed in primary health care, frequently for urinary tract infections (UTIs).

Objective: This paper presents the protocol for the first phase of the Urinary Tract Infections in Catalonia (Infeccions del tracte urinari a Catalunya) project.

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Background: Diagnostic evidence of the accuracy of a test for identifying a target condition of interest can be estimated using systematic approaches following standardized methodologies. Statistical methods for the meta-analysis of diagnostic test accuracy (DTA) studies are relatively complex, presenting a challenge for reviewers without extensive statistical expertise. In 2006, we developed Meta-DiSc, a free user-friendly software to perform test accuracy meta-analysis.

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Background: Hysterectomy, the most common gynecological operation, requires surgeons to counsel women about their operative risks. We aimed to develop and validate multivariable logistic regression models to predict major complications of laparoscopic or abdominal hysterectomy for benign conditions.

Methods: We obtained routinely collected health administrative data from the English National Health Service (NHS) from 2011 to 2018.

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Objectives: To assess the rates of SARS-CoV-2 positivity in babies born to mothers with SARS-CoV-2 infection, the timing of mother-to-child transmission and perinatal outcomes, and factors associated with SARS-CoV-2 status in offspring.

Design: Living systematic review and meta-analysis.

Data Sources: Major databases between 1 December 2019 and 3 August 2021.

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A novel learning process that does not require stimulus associations was explored in humans. The hypothesis was that two contextual stimuli taught in separate settings, with different stimuli, become equivalent if they accomplish identical functions with regard to the relations between the stimuli presented with them. The procedure consisted of : (a) first teaching an AB conditional discrimination (e.

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