Publications by Silvia E M Crivelli

Publications by authors named "Silvia E M Crivelli"

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Miravirsen (SPC3649) can inhibit the biogenesis of miR-122.

Luca F R Gebert Mario A E Rebhan Silvia E M Crivelli Rémy Denzler Markus Stoffel

Nucleic Acids Res

January 2014

MicroRNAs (miRNAs) are short noncoding RNAs, which bind to messenger RNAs and regulate protein expression. The biosynthesis of miRNAs includes two precursors, a primary miRNA transcript (pri-miRNA) and a shorter pre-miRNA, both of which carry a common stem-loop bearing the mature miRNA. MiR-122 is a liver-specific miRNA with an important role in the life cycle of hepatitis C virus (HCV).

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