Publications by authors named "Silvia Cazzanelli"
Article Synopsis
- Researchers are studying how the brain processes temperature signals, focusing on the spinal cord's dorsal horn as the initial point for encoding this thermal information.
- Using functional ultrasound imaging, the study observed brain activity in awake male mice exposed to different temperatures, uncovering a unique response pattern between the somatomotor-cingulate cortices and the hypothalamus.
- The findings suggest that the brain has a shared hub for processing temperature sensations, with the cingulate areas linked to emotional responses, especially during colder temperatures, which disrupts connectivity with the hypothalamus.
Functional ultrasound (fUS) imaging is a novel brain imaging modality that relies on the high-sensitivity measure of the cerebral blood volume achieved by ultrafast doppler angiography. As brain perfusion is strongly linked to local neuronal activity, this technique allows the whole-brain 3D mapping of task-induced regional activation as well as resting-state functional connectivity, non-invasively, with unmatched spatio-temporal resolution and operational simplicity. In comparison with fMRI (functional magnetic resonance imaging), a main advantage of fUS imaging consists in enabling a complete compatibility with awake and behaving animal experiments.
View Article and Find Full Text PDFThe cerebellum is involved in the control of voluntary and autonomic rhythmic behaviors, yet it is unclear to what extent it coordinates these in concert. We studied Purkinje cell activity during unperturbed and perturbed respiration in lobules simplex, crus 1, and crus 2. During unperturbed (eupneic) respiration, complex spike and simple spike activity encode the phase of ongoing sensorimotor processing.
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