Evaluation of a direct lymphocyte proliferation test for the diagnosis of canine food allergies with delayed reactions after oral food challenge.

Background: In humans, food allergies (FAs) are divided into those with immunoglobulin (Ig) E-mediated (immediate FA), cell-mediated (delayed FA) or both mechanisms (mixed FA). In dogs, lymphocyte stimulation tests have the highest concordance with oral food challenges (OFCs).

Objectives: To report the evaluation of a lymphocyte proliferation test (LPT) in dogs with FA and delayed reactions (≥6 h) after OFC.

Clindamycin resistance of skin derived Staphylococcus pseudintermedius is higher in dogs with a history of antimicrobial therapy.

Background: In the Netherlands there is a lack of data regarding resistance of Staphylococcus pseudintermedius to the systemic antimicrobial drugs used for the treatment of superficial pyoderma.

Objectives: To assess antimicrobial resistance, with emphasis on resistance to clindamycin and meticillin, in clinical isolates of S. pseudintermedius isolated from dogs with superficial pyoderma.

Mast cell morphometry and densitometry in experimental skin wounds treated with a gel containing adelmidrol: a placebo controlled study.

The role of skin mast cells (MCs) in wound healing has been extensively investigated. The present study was designed to examine the effect of the aliamide adelmidrol on MCs during healing of experimental cutaneous wounds. Adelmidrol gel or the vehicle alone was applied 3 times daily on 5-mm punch biopsy wounds created on the thoracolumbar skin of 10 dogs.

Assessment of the Effect of an Aliamide-containing Topical Gel by Evaluation of the Reduction of Wound Volume Measured by High R.

This study evaluated the use of an aliamide-containing gel in the treatment of skin wounds by employing noninvasive wound volume measurements acquired from wound images of high resolution ultrasonography (HRU). The dorsal thoracolumbar areas of 10 Beagle dogs were clipped and 2 rows of 6 full-thickness 5-mm punch biopsy samples were taken from either side of the midline under general anaesthesia. Wounds were allowed to heal by secondary intention, while treatment gel or base was applied 3 times daily to randomly selected treatment and control groups.

Treatment of canine Old World visceral leishmaniasis: a systematic review.

Canine visceral leishmaniasis is a systemic disease caused by Leishmania infantum. The aim of this systematic review was to identify and evaluate the evidence of efficacy of interventions for treatment or prevention of canine visceral leishmaniasis, and to propose recommendations for or against their use. Forty-seven articles describing clinical trials published between 1980 and 2004 fulfilled selection criteria.