Publications by authors named "Silvia Analia Repetto"
Parasitology
January 2022
Article Synopsis
- The study investigated the genetic variability of Strongyloides stercoralis based on a specific region of the cox1 gene from Latin-American samples, focusing on clinical outcomes following treatment with ivermectin.
- A total of 41 patients were evaluated, revealing 10 genetic haplotypes organized into two clusters; the presence of haplotypes from cluster 1 significantly increased the risk of disease reactivation post-treatment, while cluster 2 showed a substantially lower reactivation probability.
- This research is the first to analyze S. stercoralis genetic diversity in a clinical setting, highlighting the potential to enhance follow-up strategies by considering genetic information during diagnosis.
Front Vet Sci
November 2021
Article Synopsis
- A new coprological LAMP method called Copro-LAMPAc was developed to detect a zoonotic nematode affecting humans and animals, focusing on DNA extraction and primer design.
- This method demonstrated an impressive analytical sensitivity of 100 fg and a specificity of 100% when tested against DNA from hosts and other pathogens.
- When evaluated with canine fecal samples, Copro-LAMPAc proved to be more sensitive than traditional optical microscopy, positioning it as a promising tool for epidemiological studies in areas where the nematode is endemic.
Article Synopsis
- Toxocariasis is a disease primarily caused by Toxocara canis and Toxocara cati, making accurate diagnosis in dogs and cats crucial for controlling its spread.
- A new, cost-effective LAMP assay has been developed to simultaneously detect these parasites through analysis of specific mitochondrial DNA, with tests showing high sensitivity and specificity.
- This assay can be performed in basic labs and significantly reduces costs by about 80%, enabling better identification and management of toxocariasis in areas where it is common.
