Publications by authors named "Silvana Mattera"
Background And Aim: In patients with cirrhosis and small hepatocellular carcinoma (HCC), thermal ablation is currently recognized as an effective local treatment. Among thermal procedures, radiofrequency ablation (RFA) is the most diffusely used and is the standard against which any new treatment should be compared. In retrospective studies, laser ablation (LA) resulted as safe and effective as RFA.
View Article and Find Full Text PDFBackground: Previous studies have shown that laser ablation with the multifiber technique is effective in the treatment of liver tumors. However, the correct positioning of multiple needles may be challenging.
Purpose: To investigate the use of a novel needle guide system that was developed to perform percutaneous laser ablation of liver tumors with the multifiber technique under ultrasonographic guidance.
Article Synopsis
- The incidence of hepatocellular carcinoma (HCC) is rising globally, with an increasing number of older patients likely to be affected.
- A study was conducted to evaluate how age influences the effectiveness and tolerability of sorafenib in treating advanced HCC among patients with cirrhosis.
- Results showed that while older patients had longer progression-free and overall survival times compared to younger patients, severe treatment-related side effects were more common in the younger group, indicating that sorafenib is equally effective and safe for older patients.
Background: Sorafenib is currently the only approved systemic treatment for hepatocellular carcinoma.
Aim: to evaluate safety and effectiveness of sorafenib in the field of practice.
Methods: We report a single-centre experience on 116 advanced hepatocellular carcinoma patients treated with sorafenib between February 2008 and March 2011.