Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after subchronic exposure.

Paracetamol is one of the most widely sold non-prescription drugs. This study aimed to evaluate the effects of the paracetamol on reproductive, biochemical, genetic, histopathological and hematogical biomarkers by waterborne exposure. Male fish of Rhamdia quelen were exposed to environmental concentrations of paracetamol (0, 0.

Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats.

Purpose: To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use.

Methods: Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period.

Pierre Robin Sequence: A Familial, Clinical, and Pathoanatomical Record of an Affected Dachshund.

This study describes a spontaneous case of Pierre Robin sequence in a nonhuman animal species. A miniature dachshund with micrognathia developed glossoptosis, respiratory distress, dysphagia, temporomandibular ankylosis, and a misaligned upper jaw. The severity of this condition resulted in death by obstructive apnea at the age of 8 mo.

Nonsyndromic cleft lip and palate in boxer dogs: evidence of monogenic autosomal recessive inheritance.

Four newborn boxer dogs with bilateral cleft lip and palate were examined in search of further abnormalities, but no other type of congenital defect was found. These data, along with the pedigree inspection regarding the clinical phenotype, led to the conclusion that the affected dogs had a nonsyndromic monogenic autosomal recessive cleft lip and palate.

Follicular dysplasia of the adult doberman pinscher.

This paper presents the case of an adult female, red Doberman pinscher affected by permanent hypotrichosis, limited to the dorsolumbar region and sides of the trunk. The hypotrichosis began at approximately the age of 2 years and progressed slowly with no skin hyperpigmentation. The clinical and histopathological characteristics are of an uncommon form of follicular dysplasia.

VACTERL association in a cat.

We describe a female domestic cat with apparent VATER/VACTERL association, including vertebral abnormalities, anal atresia, radial agenesis, and cardiovascular and renal defects. If we consider the acronym VATER, this cat had a triad (VAR); however, if we consider the extended acronym VACTERL, she had a pentad (VACRL).

Clinical and genetic aspects of X-linked ectodermal dysplasia in the dog -- a review including three new spontaneous cases.

This review presents the clinical, dermato-histopathological and genetic features of canine X-linked ectodermal dysplasia in previously reported cases and in three new spontaneous cases. The condition is compared with anhidrotic ectodermal dysplasia in humans and, based on current genetic concepts, we suggest that the two conditions are caused by the same gene and, consequently, represent a single pathological entity that affects both humans and dogs.