HPV immunohistochemical testing and cervical dysplasia.

Background And Aim: HPV (Human Papilloma Virus) infection represents a necessary condition for cervical carcinogenesis. The purpose of this study was to evaluate the efficiency of HPV testing using an immunohistochemical staining kit with implications upon both diagnosis and treatment of cervical intraepithelial neoplasia (CIN).

Methods: Seventy-nine patients and eighty-six controls were enrolled in the study.

TNF-α 308 G/A polymorphism and cervical intraepithelial neoplasia.

Aim: The purpose of the present study was the analysis of the relationship between tumor necrosis factor-α (TNF-α) -308 G/A and cervical intraepithelial neoplasia (CIN).

Materials And Methods: A prospective case-control study was performed, enrolling 78 cases of cervical intraepithelial neoplasia and 107 controls. Every patient had a complete gynecological examination with cervical sampling and colposcopy and TNF-α 308 G/A genotyping.