Publications by authors named "Silva Westmore"
IL6 genetic variants haplotype is associated with susceptibility and disease activity but not with therapy response in patients with inflammatory bowel disease.
Beatriz Piantoni Gonçalves Tamires Flauzino Cláudia Junko Inoue Jaqueline Costa Castardo de Paula Talita Cristina Galvão Silva Westmore
Int J Colorectal Dis
February 2021
Purpose: The aim of the present study was to evaluate the IL6 -174 G>C (rs1800795) and -572 G>C (rs1800796) genetic variants and their association with inflammatory bowel diseases (IBDs), disease activity, and response to TNF-α inhibitors.
Methods: The study included 178 patients with IBD and 224 healthy controls. Among the IBD patients, 66 of them were in use of TNF-α inhibitors therapy and were followed during 48 weeks and categorized as responders and non-responders.