A Gelatin-Based Biomimetic Scaffold Promoting Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells.

Background: In bone tissue engineering segment, numerous approaches have been investigated to address critically sized bone defects via 3D scaffolds, as the amount of autologous bone grafts are limited, accompanied with complications on harvesting. Moreover, the use of bone-marrow-derived stem cells is also a limiting factor owing to the invasive procedures involved and the low yield of stem cells. Hence, research is ongoing on the search for an ideal bone graft system promoting bone growth and regeneration.

Ingenuity in pattern recognition: a novel bioinformatics approach towards lung cancer identification.

Lung cancer is the significant contributor of increased cancer deaths. Earlier research indicates that the environmental factors have a major role in causing lung cancer. It is evident that the pathway of lung cancer includes both RAS-mediated and non-RAS-mediated mechanisms.