Publications by authors named "Silke Nurmohamed"
Article Synopsis
- The study explores the use of engineered cartilage models to promote bone regeneration through a process called endochondral bone regeneration (EBR) in a large animal model.
- It involves inducing cartilage formation in goat-derived cells and creating two different biomaterials that simulate various stages of soft callus development.
- Results showed that the more advanced biomaterial led to significant bone regeneration similar to traditional grafting methods, highlighting potential for future clinical applications in humans.
Objectives: The aim of this study was the preclinical and clinical evaluation of osteoinductive calcium phosphate with submicron surface topography as a bone graft substitute for maxillary sinus floor augmentation (MSFA).
Material And Methods: A preclinical sheep model of MSFA was used to compare a calcium phosphate with submicron needle-shaped topography (BCP , MagnetOs Granules, Kuros Biosciences BV) to a calcium phosphate with submicron grain-shaped topography (BCP ) and autologous bone graft (ABG) as controls. Secondly, a 10-patient, prospective, randomized, controlled trial was performed to compare BCP to ABG in MSFA with two-stage implant placement.
A 79-year-old man, an 81-year-old woman and a 60-year-old woman were referred to our oral and maxillofacial surgery clinic with a large submandibular swelling. All three patients had a history of prior excision of a small carcinoma of the lower lip. Primary treatment had been carried out by a number of different medical specialists.
View Article and Find Full Text PDF