Universal screening for Lynch syndrome in endometrial cancer diagnoses in Auckland, New Zealand: The initial experience.

Background: Universal mismatch repair immunohistochemistry (MMR IHC) tumour testing in endometrial cancer (EC) for Lynch syndrome (LS) was introduced in Auckland, New Zealand, in January 2017. Identifying patients with LS allows them and their families to access risk reduction strategies. Universal MMR IHC testing aids in the molecular classification of EC and has prognostic and therapeutic implications.

Intravascular leiomyomatosis with extension to the inferior vena cava.

Intravascular leiomyomatosis (IVL) is a rare benign smooth muscle neoplasm growing within the pelvic venous system, often with caval and intracardiac extension. It frequently coexists with uterine leiomyomas or occurs in women with a history of myomectomy or hysterectomy. IVL is often asymptomatic until intracardiac extension occurs, and carries a risk of sudden death, necessitating timely diagnosis and management.

Gestational weight gain in a multi-ethnic sample of pregnant women from Counties Manukau Health, Auckland, New Zealand.

Aim: High and low gestational weight gain (GWG) adversely affects perinatal outcomes, and impacts long-term maternal and child health. Our aim is to report i) GWG categories by 2009 Institute of Medicine guidelines in the multi-ethnic population in Counties Manukau Health, ii) demographic factors and iii) adverse perinatal outcomes associated with high and low GWG.

Method: Women with singleton pregnancy and weight recorded at ≤20 weeks and again in the third trimester comprised the study population.