A seven-immune-genes risk model predicts the survival and suitable treatments for patients with skin cutaneous melanoma.

Background: Skin cutaneous melanoma is characterized by high malignancy and prognostic heterogeneity. Immune cell networks are critical to the biological progression of melanoma through the tumor microenvironment. Thus, identifying effective biomarkers for skin cutaneous melanoma from the perspective of the tumor microenvironment may offer strategies for precise prognosis prediction and treatment selection.

Complication Rates after Breast Surgery with the Motiva Smooth Silk Surface Silicone Gel Implants-A Systematic Review and Meta-Analysis.

Background: In an era where textured devices are being phased out due to concerns about BIA-ALCL, the Motiva SilkSurface breast implants intend to alleviate historical prosthesis-related complications. However, its safety and feasibility remain unelucidated.

Methods: An analysis of Pubmed, Web of Science, Ovid, and Embase databases was performed.

Research on the Governance Relationship among Stakeholders of Construction Waste Recycling Based on ANP-SNA.

A method based on Analytic Network Process and Social Network Analysis (ANP-SNA) was proposed in this paper to determine and better clarify the governance relationship among various stakeholders involved. Firstly, fourteen stakeholders of construction waste recycling were identified using the snowball sampling method, and the governance relationships of these stakeholders were summarized into four aspects with eight indicators. Secondly, the weights of the stakeholder governance relationship indicators were determined based on Analytic Network Process (ANP).

Chances and challenges-analysis of trends in breast reconstruction.

Introduction: While breast reconstruction has become more and more important within the past decade, research focus areas as well as trends are in constant change.

Method: The publications from 2012 to 2021 were retrieved from the Web of Science Core Collection database. CiteSpace visualization analysis software was used to analyze the institutions, countries, regions, categories, and keywords on breast reconstruction research.

Levels of Coenzyme Q and Several COQ Proteins in Human Astrocytoma Tissues Are Inversely Correlated with Malignancy.

In a previous study, we reported the alterations of primary antioxidant enzymes and decreased citrate synthase (CS) activities in different grades of human astrocytoma tissues. Here, we further investigated coenzyme Q (CoQ) levels and protein levels of polyprenyl diphosphate synthase subunit (PDSS2) and several COQ proteins required for CoQ biosynthesis in these tissues. We found that the level of endogenous CoQ, but not of exogenous α-tocopherol, was higher in nontumor controls than in all grades of astrocytoma tissues.

Breast Reconstruction- Developing a Volumetric Outcome Algorithm.

Postoperative loss of breast volume represents a significant parameter for outcome evaluation of breast reconstruction. Breast volume broadly varies- depending of reconstruction method as well as surgical differences. A structural pattern of breast volume loss provides an essential parameter for preoperative design, helps to reduce postoperative breast asymmetry rate and thereby the need for reoperation.

Volumetry in Breast Reconstruction: Always New, Always Better?

Although breast surgeries for aesthetic or reconstructive purposes are regularly performed, no focus has been laid on establishing an adequate and reliable volumetry method. While CT and MRI scan represent methods that are already in clinical use, the 3D scan  is a novel and promising tool, easy to use with the possibility to measure the anatomic breast volume in an upright position. Nevertheless, its reliability is broadly underinvestigated.

Understanding Breast Implant Illness: Etiology is the Key.

Because breast augmentation is one of the most popular cosmetic procedures, the issue of implant-related complications has been widely debated ever since the FDA approved the use of implants in 1962. Although decades have passed, breast implant illness (BII) still represents a poorly defined and controversial complication. With ongoing nonscientific discussion in the mainstream media and on social media, revealing the etiology of BII is urgent because knowledge of this subject ultimately influences patients' decisions.

Starch physicochemical properties of double recessive sweet-waxy maize.

Sweet-waxy is a new type of maize with waxy and sugary double recessive genes. This study aims to clarify starch structural and functional properties of this maize type. Grains with sweet-waxy and waxy phenotypes were separated from an ear using the two sweet-waxy maize hybrids of ATN and NKY as materials.

Characterization of human mitochondrial PDSS and COQ proteins and their roles in maintaining coenzyme Q levels and each other's stability.

Mutations of many PDSS and COQ genes are associated with primary coenzyme Q (CoQ) deficiency, whereas mitochondrial DNA (mtDNA) mutations might cause secondary CoQ deficiency. Previously, we found that COQ5 and COQ9 proteins are present in different protein complexes in the mitochondria in human 143B cells and demonstrated that COQ5 and COQ9 knockdown suppresses CoQ levels. In the present study, we characterized other PDSS and COQ proteins and examined possible crosstalk among various PDSS and COQ proteins.