Publications by authors named "Sikder Nahidul Islam Rabbi"

Introduction: Nephrotic syndrome is a common pediatric kidney disease. Investigations on several genetic polymorphisms revealed an inconsistent influence on the resistance of patients to steroids.

Objectives: This study aimed to identify the association of (1236C > T, 2677G > T, 3435C > T), (rs10482634, rs6877893), and (CYP3A5*3) gene polymorphism as well as sociodemographic and clinicopathological parameters with the risk of developing prednisolone resistance in pediatric patients with nephrotic syndrome.

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Article Synopsis
  • Antithrombotic agents like aspirin and clopidogrel are essential for patients with arterial thrombosis, especially after procedures like percutaneous coronary intervention (PCI), prevalent in Bangladesh.
  • The study aimed to evaluate genetic variations (polymorphisms) in the CYP2C19 and ITGB3 genes among 1,000 patients with cardiovascular disease who were treated with these medications.
  • Results showed significant prevalence of CYP2C19 polymorphisms (64.1% for CYP2C19*2 and 22.7% for CYP2C19*17) in clopidogrel-treated patients and high rates of ITGB3 polymorphisms in those taking aspirin, suggesting the importance of genetic testing for
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Lung cancer is one of the most frequently occurring cancers throughout the world as well as in Bangladesh. This study aimed to correlate the prognostic and/or predictive value of functional polymorphisms in SULT1A1 (rs9282861) and XRCC1 (rs25487) genes and lung cancer risk in Bangladeshi population. A case-control study was conducted which comprises 202 lung cancer patients and 242 healthy volunteers taking into account the age, sex, and smoking status.

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