Clinical Outcomes of Extended Versus Intermittent Infusion of Piperacillin/Tazobactam in Critically Ill Patients: A Prospective Clinical Trial.

Study Objective: To determine whether critically ill patients receiving extended-infusion (EI) piperacillin/tazobactam would have improved clinical outcomes compared with patients receiving intermittent infusions.

Design: Single-center, open-label, prospective study.

Setting: Twenty-two-bed intensive care unit (ICU) in a regional hospital in Hong Kong.