Two different mirror neuron pathways for social and non-social actions? A meta-analysis of fMRI studies.

Mirror neurons (MNs) represent a class of neurons that are activated when performing or observing the same action. Given their role in social cognition and previous research in patients with psychiatric disorders, we proposed that the human MN system (MNS) might display different pathways for social and non-social actions. To examine this hypothesis, we conducted a comprehensive meta-analysis of 174 published human functional magnetic resonance imaging studies.

A common self-advantage across the implicit and explicit levels for self-body recognition.

Introduction: Although self-bias has been extensively studied and confirmed in various self-related stimuli, it remains controversial whether self-body can induce recognition advantage at the explicit level. After careful examination of previous experiments related to self-body processing, we proposed that participant strategies may influence explicit task outcomes.

Methods: To test our hypothesis, we designed a novel explicit task.

Cellular uptake of nickel by NikR is regulated by phase separation.

Bacterial cells were long thought to be "bags of enzymes" with minimal internal structures. In recent years, membrane-less organelles formed by liquid-liquid phase separation (LLPS) of proteins or nucleic acids have been found to be involved in many important biological processes, although most of them were studied on eukaryotic cells. Here, we report that NikR, a bacterial nickel-responsive regulatory protein, exhibits LLPS both in solution and inside cells.

Defining the Pluripotent Marker Genes for Identification of Teleost Fish Cell Pluripotency During Reprogramming.

Pluripotency is a transient state in early embryos, which is regulated by an interconnected network of pluripotency-related genes. The pluripotent state itself seems to be highly dynamic, which leads to significant differences in the description of induced pluripotent stem cells from different species at the molecular level. With the application of cell reprogramming technology in fish, the establishment of a set of molecular standards for defining pluripotency will be important for the research and potential application of induced pluripotent stem cells in fish.

Fish Pluripotent Stem-Like Cell Line Induced by Small-Molecule Compounds From Caudal Fin and its Developmental Potentiality.

The technique of induced pluripotent stem cells has significant application value in breeding and preserving the genetic integrity of fish species. However, it is still unclear whether the chemically induced pluripotent stem cells can be induced from non-mammalian cells or not. In this article, we first verify that fibroblasts of fish can be chemically reprogrammed into pluripotent stem cells.