Publications by authors named "Sijia Pu"
Background And Objective: Treating recurrent atrial arrhythmias after persistent atrial fibrillation (PeAF) ablation is often challenging. This single-center, prospective study aimed to observe the effectiveness of different combinations of oral antiarrhythmic drugs (AADs) in reverting to sinus rhythm (SR) in patients with recurrent atrial arrhythmias after PeAF ablation.
Methods: Forty-five patients who experienced recurrent atrial arrhythmias after PeAF ablation were included.
Article Synopsis
- The study reviewed how CTLA-4 inhibitors, while effective for treating malignancies, are linked to increased cardiovascular adverse events in patients.
- An analysis of 20 clinical trials revealed that these inhibitors significantly raised the incidence of all-grade cardiovascular issues, especially when used alone, leading to notably higher rates of severe cardiovascular complications.
- Despite the added risks, combining CTLA-4 inhibitors with other treatments like chemotherapy or PD-1/PD-L1 inhibitors did not further increase cardiovascular toxicity compared to those not receiving CTLA-4 inhibitors.
Background: The risks of cardiovascular disease (CVD) and CVD mortality are prevalent among cancer survivors (CS) population. The 2022 ESC Guidelines on cardio-oncology have recommended that modifying cardiovascular risk factors (CVRF) could potentially improve long-term outcomes in CS.
Objectives: To identify the independent and joint chronic kidney disease (CKD) associations of hyperuricemia with the incidence of CVD and mortality outcomes among CS.
Background: Previously, ablation at the outflow tract was considered to be safe and rarely affected the His-Purkinje system due to their spatial distance. However, we have reported a case of right bundle branch block (RBBB) and junctional beats that were recorded during radiofrequency catheter ablation in a patient who had a history of peri-membranous ventricular septal defect (pmVSD) closure and the implantation of a metallic occluder.
Case Summary: A 16-year-old girl with a metallic occluder for peri-membranous ventricular septum defect underwent an ablation procedure for premature ventricular complexes.
Aims: Pulsed field ablation (PFA) is emerging as a non-thermal, tissue-specific technique for pulmonary vein isolation (PVI) in atrial fibrillation therapy. This pre-clinical study aims to investigate the feasibility and safety of PVI using a novel PFA system including a nanosecond-scale PFA generator, a novel lotos PFA catheter, and a customized 12 Fr steerable sheath.
Methods And Results: A total of 11 Yorkshire swine were included in this study, with 4 in the acute cohort and 7 in the chronic cohort.
Background And Objective: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States. However, current evidence on the association between muscle quality and CVD is limited. This study investigates the potential association between the muscle quality index (MQI) and the prevalence of CVD and CVD-related mortality.
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- A study conducted in Guangzhou, China, found the overall prevalence of heart failure (HF) among community residents aged 35 and over was 1.06%, with men at a higher risk.
- The research indicated that age, atrial fibrillation, valvular heart disease, and chronic conditions like hypertension significantly increased the odds of developing HF.
- HF incidence was notably higher among individuals aged 65 and above, suggesting that managing existing cardiovascular conditions could help lower the risk of HF in this population.
Objective: The purpose of this study was to evaluate the difference in effectiveness and safety of high-power, short-duration (HPSD) radiofrequency catheter ablation (RFA) guided by relatively low ablation index (AI) values and conventional RFA in paroxysmal atrial fibrillation (PAF) patients.
Methods: The HPSD RFA strategy (40-50 W, AI 350-400 for anterior, 320-350 for posterior wall; = 547) was compared with the conventional RFA strategy (25-40 W, without AI; = 396) in PAF patients who underwent their first ablation. Propensity-score matching analyses were used to compare the outcomes of the two groups while controlling for confounders.
Aim: We aimed to evaluate the effectiveness and safety between high-power short-duration (HPSD) radiofrequency ablation (RFA) and conventional RFA in patients with atrial fibrillation (AF).
Methods: Studies comparing HPSD and traditional applications in patients undergoing initial catheter ablation for atrial fibrillation from inception through December 2021 were searched on Pubmed, Medline, Cochrane, and Clinicaltrials.gov.
Background And Objectives: Patients with systemic lupus erythematosus (SLE) might have increased risk of atrial fibrillation (AF) as a result of initiating chronic and systematic inflammation. However, the prevalence of AF in patients with SLE have not been well quantified. The aim of this systematic review and meta-analysis was to collect and identify available clinical data to explore this possible correlation.
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