Publications by authors named "Siji Nojin Paul"
Purpose: Magnetic resonance (MR) imaging is the gold standard in image-guided brachytherapy (IGBT) due to its superior soft-tissue contrast for target and organs-at-risk (OARs) delineation. Accurate and fast segmentation of MR images are very important for high-quality IGBT treatment planning. The purpose of this work is to implement and evaluate deep learning (DL) models for the automatic segmentation of targets and OARs in MR image-based high-dose-rate (HDR) brachytherapy for cervical cancer.
View Article and Find Full Text PDFPurpose: The purpose of this study was to report clinical outcomes in patients treated with accelerated partial breast irradiation (APBI), stratified as per molecular subtype and American Society for Therapeutic Radiology and Oncology/Groupe Européen de Curiethérapie and European Society for Radiotherapy & Oncology (ASTRO/GEC-ESTRO) patient selection criteria in order to determine whether molecular subtype should be recommended as one of the selection criteria for APBI.
Material And Methods: 157 early-stage breast cancers patients, treated with APBI using multi-catheter interstitial brachytherapy with ≥ 6 months follow-up were included. Molecular subtype was assigned based on estrogen/progesterone receptor (ER/PR), Her2neu and tumor grade.
Interobserver Variability in the Delineation of Gross Tumour Volume and Specified Organs-at-risk During IMRT for Head and Neck Cancers and the Impact of FDG-PET/CT on Such Variability at the Primary Site.
J Med Imaging Radiat Sci
June 2017
Purpose: To assess interobserver variability (IOV) in the delineation of structures during intensity-modulated radiation therapy for head and neck squamous cell carcinoma and the impact of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) on such variability at the primary site.
Methods: Three experienced head-neck radiation oncologists, blinded to each other, delineated the primary site gross tumour volume (GTV) and specified organs-at-risk (OARs) viz parotid gland, spinal cord, and cochlea in 10 patients with pharyngolaryngeal cancers suited for definitive intensity-modulated radiation therapy. IOV was assessed by concordance index (CI), Dice similarity coefficient (DSC), and Fleiss' kappa.
Aim: The present study was to investigate the use of MOSFET as an vivo dosimeter for the application of Ir-192 HDR brachytherapy treatments.
Material And Methods: MOSFET was characterized for dose linearity in the range of 50-1000 cGy, depth dose dependence from 2 to 7 cm, angular dependence. Signal fading was checked for two weeks.
Purpose: To evaluate the impact of needle displacements on quality indices during multifractionated pelvic interstitial brachytherapy (IBT).
Methods And Materials: Patients undergoing boost IBT were included. Postprocedure planning and verification CT scans were obtained.
Glioblastoma progenitor or stem cells residing in the stem-cell niche in the subventricular zones (SVZ) can initiate or promote tumorigenesis. They can also migrate throughout the brain, resulting in disease progression. Irradiation of potential cancer stem-cell niche in the SVZ may influence survival.
View Article and Find Full Text PDFPurpose: To evaluate three-dimensional needle displacements during multifractionated interstitial brachytherapy (BT) for cervical cancers.
Methods And Materials: Patients scheduled to undergo pelvic interstitial BT for postoperative and or postradiation vault recurrences were included from November 2009 to December 2010. All procedures were performed under spinal anesthesia.