Unveiling anharmonic scattering in van der Waals semiconductor GaPS through Raman spectroscopy and theoretical calculation.

The van der Waals thiophosphate GaPS presents additional opportunities for gallium-based semiconductors, but limited research on phonon interactions has hindered optimization on thermal properties. This research undertakes a comprehensive investigation into the anharmonic phonon scattering within GaPS. The findings reveal pronounced anharmonic scattering, with both cubic and quartic phonon scatterings significantly influencing phonon redshift and broadening.

Rapid Assembly of Ultrafine Palladium Nanoparticle-Decorated HOF-101 Triggered by Guest Enzyme Encapsulation.

Rapid enzyme immobilization is essential for enzyme catalysis and sensing applications, yet constructing effective immobilization systems is challenging due to the need to balance enzyme activity with the properties of the surrounding framework. Herein, taking glucose oxidase (GOx) as a model, a rapid and straightforward approach was presented for synthesizing palladium nanoparticles (PdNPs)-decorated GOx encapsulated in HOF-101 nanocomposite materials (designated as PdNPs/GOx@HOF-101) through an in situ photoreduction and enzyme-triggering HOF-101 encapsulation. The enzyme's surface residues trigger the nucleation of HOF-101 around it through the hydrogen-bonded bio interface, completing the self-assembly of HOF-101 in 0.

Coencapsulating TMB Probes and Bimetallic MOF Nanozymes in a Hydrogel Patch for Fabricating Reusable Visual VC Sensors.

As a typical chromogenic probe, 3,3',5,5'-tetramethylbenzidine (TMB) has been widely applied in the field of visual detection due to its low toxicity and highly sensitive response. Due to the hydrophobic nature of TMB, encapsulating it into a hydrogel, which serves as an ideal matrix for wearable sensors, presents significant challenges that complicate the fabrication of visual wearable devices. Herein, the TMB probe and bimetallic MOF nanozymes are coencapsulated in a hydrogel patch for the fabrication of reusable visual sensors.

Continuous Tunable Energy Band Tailoring Boosts Extending the Sensing of the Waveband Based on (InGa)O Solar-Blind Photodetectors.

Rising wide bandgap semiconductor gallium oxide (GaO) displays huge potential in performing solar-blind photodetection, with constraint in narrow detection wavebands in nature, whereas bandgap modulation through the introduction of exotic atoms into GaO has an essential effect on the tunable performance of photodetectors and the detection waveband. Here, a novel method for the preparation of (InGa)O alloy films is proposed, and the continuous tuning of the bandgap in the range of 3.70-4.

Menin Deficiency Induces Autism-Like Behaviors by Regulating Foxg1 Transcription and Participates in Foxg1-Related Encephalopathy.

FOXG1 syndrome is a developmental encephalopathy caused by FOXG1 (Forkhead box G1) mutations, resulting in high phenotypic variability. However, the upstream transcriptional regulation of Foxg1 expression remains unclear. This report demonstrates that both deficiency and overexpression of Men1 (protein: menin, a pathogenic gene of MEN1 syndrome known as multiple endocrine neoplasia type 1) lead to autism-like behaviors, such as social defects, increased repetitive behaviors, and cognitive impairments.

Assessment of the Reliability and Clinical Applicability of ChatGPT's Responses to Patients' Common Queries About Rosacea.

Objective: Artificial intelligence chatbot, particularly ChatGPT (Chat Generative Pre-trained Transformer), is capable of analyzing human input and generating human-like responses, which shows its potential application in healthcare. People with rosacea often have questions about alleviating symptoms and daily skin-care, which is suitable for ChatGPT to response. This study aims to assess the reliability and clinical applicability of ChatGPT 3.

Tunable GaOsolar-blind photosensing performance via thermal reorder engineering and energy-band modulation.

As an ultra-wide bandgap semiconductor, gallium oxide (GaO) has been extensively applied in solar-blind photodetectors (PDs) owing to the absorbance cut-off wavelength of shorter than 280 nm, and the optimized technologies of detection performance is seriously essential for its further usages. Herein, a feasible thermal reorder engineering method was performed through annealing GaOfilms in vacuum, Oand oxygen plasma atmospheres, realizing to tune solar-blind photosensing performance of GaOPDs. Thermal treatment, in fact a crystal reorder process, significantly suppressed the noise in GaO-based PDs and enhanced the photo-sensitivity, with the dark current decreasing from 154.

Construction of a plasmid-free L-leucine overproducing Escherichia coli strain through reprogramming of the metabolic flux.

Background: L-Leucine is a high-value amino acid with promising applications in the medicine and feed industries. However, the complex metabolic network and intracellular redox imbalance in fermentative microbes limit their efficient biosynthesis of L-leucine.

Results: In this study, we applied rational metabolic engineering and a dynamic regulation strategy to construct a plasmid-free, non-auxotrophic Escherichia coli strain that overproduces L-leucine.

[Efficient production of biliverdin through whole-cell biocatalysis using recombinant ].

Biliverdin is an important cellular antioxidant. Traditionally, biliverdin is produced by chemical oxidation of bilirubin, which is a complex process and the final product is of low purity. Here we report an efficient, green and safe process for biotechnological production of biliverdin.

Effectiveness of VISIA system in evaluating the severity of rosacea.

Background: Rosacea is a facial chronic inflammatory skin disease with almost 5.5% prevalence. Although there are various scales of rosacea, they are objective and discordant among different dermatologists.

[Engineering the C4 pathway of Corynebacterium glutamicum for efficient production of 5-aminolevulinic acid].

5-aminolevulinic acid (5-ALA) plays an important role in the fields of medicine and agriculture. 5-ALA can be produced by engineered Escherichia coli and Corynebacterium glutamicum. We systematically engineered the C4 metabolic pathway of C.