Publications by authors named "Sihan Hou"

Article Synopsis
  • This study investigates the relationship between changes in microbial communities in the lungs and gut of a rat model for idiopathic pulmonary fibrosis (IPF) to understand how these changes may relate to disease mechanisms.
  • Researchers found significant differences in microbial composition in the lung and gut of IPF model rats when compared to control rats, indicating a potential link between microbial shifts and IPF.
  • Mediation analysis identified specific physiological indices, such as hydroxyproline and mean corpuscular volume, that connect lung and gut microbial genera, revealing complex interactions that could contribute to IPF pathology through the "gut-lung axis."
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The continuous decline of human semen quality during the past decades has drawn much concern globally. Previous studies have suggested a link between abnormal BMI and semen quality decline, but the results remain inconsistent. This systematic review and meta-analysis aimed to evaluate the association between body mass index (BMI) and semen quality.

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The impact of dietary saturated fatty acids (SFAs) on breast cancer risk may vary depending on their carbon chain lengths, attributable to the discrepancy in their dietary sources and biological activities. The associations between SFA subgroups classified by chain length and breast cancer risk remain controversial. In this case-control study, we aimed to investigate the association between the dietary intake of SFA subgroups, classified by chain lengths, and odds of breast cancer in China.

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Background: The effect of exposure to extreme temperature events (ETEs) on dementia mortality remains largely unknown. We aimed to quantify the association of ETE exposure with dementia mortality.

Methods: We conducted a population-based, case-crossover study among 57 791 dementia deaths in Jiangsu province, China, during 2015-20.

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The lung microbiota have been found to be substantially altered in numerous pulmonary disorders, and crosstalk between the host pathophysiology and lung microbiota plays critical roles in the regulation of disease states. The aim of this study was to investigate dynamic changes in the lung microbiota during different stages of acute lung injury and acute respiratory distress syndrome (ALI/ARDS). Rats receiving an intraperitoneal administration of lipopolysaccharide (LPS) were sacrificed at 12 and 48 h after injection, and the hematological parameters, serum cytokine levels, and histological characteristics of the lung tissue and lung microbiota were assessed.

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Silk gland is an organ that produces and secretes silk proteins. The development of the silk gland is essential for high silk production yield and silk quality. Although Sage reportedly plays a pivotal role in embryonic silk gland development, the mechanism underlying its action remains unclear.

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The number of cells in tissues is under strict genetic control, and research on the determination of cell number is of great importance to understand the growth and development of organs. Bmsage, a bHLH transcription factor, is involved in the development of the silk gland during the embryonic stage in Bombyx mori. However, the mechanism by which it influences silk gland development is unclear.

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