Publications by authors named "Siham Rouf"
Background: Managing type 1 diabetes in school is a real challenge for teachers, parents, and students themselves. Involving school educators in providing care and support is becoming more of a necessity than a luxury to facilitate access to healthcare services in schools for children with type 1 diabetes.
Objectives: Our work aimed to assess the background knowledge of teachers on type 1 diabetes and evaluate the impact of an educational intervention in improving this knowledge.
Is there any association between vitamin D status and PCOS disease?
Gynecol Endocrinol
December 2024
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a widespread hormonal disorder in women of reproductive age, and this study focused on evaluating vitamin D levels in women with PCOS compared to healthy controls.
- The study analyzed 176 women, finding that 40.2% of those with PCOS had vitamin D deficiency, significantly higher than the 24% observed in healthy controls, and those with both PCOS and obesity or insulin resistance had even lower vitamin D levels.
- The research suggests that vitamin D deficiency may play a role in the development of PCOS, particularly in women with obesity or insulin resistance, indicating that vitamin D supplementation could be helpful in managing the condition.
A thyroid nodule is managed according to the clinical context, ultrasound (US) findings, and fine needle aspiration (FNA) results. Most thyroid nodules are benign; however, nodule classification is crucial to avoid unnecessary thyroid surgery. We conducted this study to compare the findings of fine-needle aspiration cytology (FNAC) expressed using the Bethesda system with the features of thyroid US classified using the EU-TIRADS classification to assess the risk of malignancy.
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- * Cutis verticis gyrate (CVG) is a rare skin complication seen in some acromegaly patients, characterized by the abnormal growth of scalp skin resulting in folds and furrows.
- * Treatment involves managing growth hormone and IGF1 levels through surgery or injections, and the diagnosis of CVG is primarily clinical, requiring no imaging.
Apoplexy of a giant clival ectopic prolactinoma: A very rare case report.
Int J Surg Case Rep
July 2024
Introduction And Importance: Ectopic pituitary neuroendocrine tumor (EPNET) is a very rare entity, seldom with apoplexy evolution. Only three cases of intracranial ectropic pituitary neuroendocrine tumor apoplexy were reported in the literature.
Case Presentation: We report the case of a 45-year-old woman with a history of amenorrhea, and headaches.
Background: Biliary complications are frequent in patients with acromegaly. These complications may be secondary either to acromegaly or to somatostatin analogs (SAs). We aimed in this paper to assess the prevalence of biliary complications in patients with acromegaly at diagnosis and after treatment with SAs.
View Article and Find Full Text PDFIntroduction: Malignant insulinoma is a rare neuroendocrine tumor responsible for excessive insulin secretion and life-threatening hypoglycemia episodes. Computed tomography (CT) of the abdomen can identify a pancreatic tumor corresponding to insulinoma. Loco-regional metastases define the metastatic cases.
View Article and Find Full Text PDFIntroduction And Importance: Lymphocytic hypophysitis is an underestimated disease and the pathogenesis is still poorly elucidated. Post-coronavirus lymphocytic hypophysitis is a new emerging entity.
Case Presentation: A 16-year-old previously healthy girl presented with pituitary tumor syndrome.
Introduction And Importance: Tuberculosis of the central nervous system is unusual and accounts for 1 % of all cases of tuberculosis in the world. The pituitary location is even scarcer.
Case Presentation: A 14-year-old girl presented with polyuria-polydipsia syndrome and menstrual irregularity.
Article Synopsis
- Diabetic retinopathy (DR) is a serious and common complication of diabetes that can lead to vision loss, particularly in younger individuals, and often goes unnoticed until significant problems arise.
- A study conducted with 359 type 1 diabetes patients in Morocco found that 30% of them had DR, with varying levels of severity based on their duration of diabetes and poor blood sugar control.
- Findings indicated that longer diabetes duration, as well as the presence of neuropathy and nephropathy, are significant risk factors for developing DR, suggesting the need for collaboration between diabetes and eye care specialists for early detection and treatment.
Objectives: Our study aimed to compare the efficacy of transdermal dihydrotestosterone and testosterone enanthate in treating idiopathic micropenis.
Patients And Methods: It's a comparative randomized study of 49 patients with idiopathic micropenis who are followed up in the Endocrinology-Diabetology and Nutrition Department of Mohammed VI University Hospital Center of Oujda, Morocco. The study was conducted from December 2019 to April 2021.
Introduction And Importance: Phaeochromocytomas and paragangliomas are rare neuroendocrine neoplasms that grow outside the adrenal gland and arise from the primitive neural crest cells. The retroperitoneal location is extremely rare with an incidence of 2-8 per million.
Case Presentation: Here we report a case of an 80 years old man presenting with abdominal pain and vomiting associated with hypertensive peaks and weight loss.
Fahr's syndrome is defined by the presence of striato-pallido-dentate calcifications. It is a rare entity with clinical polymorphism, and it occurs in patients with dysparathyroidism, especially those with hypoparathyroidism. It must be distinguished from Fahr's disease (FD), which is defined by the presence of intracerebral calcifications without phosphocalcic metabolism abnormality.
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- Non-functional pituitary carcinoma is a rare type of tumor that spreads without causing hormonal overproduction, and few cases have been documented.
- A case study highlighted a 48-year-old woman who experienced spinal pain and was found to have non-functional pituitary carcinoma after surgery and examination.
- Distinguishing between non-functional pituitary adenomas and carcinomas is difficult, and managing these tumors usually requires a combination of surgery, chemotherapy, and radiotherapy.
Article Synopsis
- The study investigates the rising incidence of Type 1 diabetes mellitus (T1DM) and examines the role of 25OHD (vitamin D) deficiency as a potential trigger for the disease.
- A case-control analysis was conducted with 147 T1DM patients under 19 years old compared to 147 matched controls, revealing lower average serum 25OHD levels in T1DM patients (15.02 ng/ml) versus controls (19.29 ng/ml).
- Findings indicate a significant negative correlation between HbA1c (a measure of diabetes control) and serum 25OHD levels, emphasizing the need for awareness and potential vitamin D supplementation in children and adolescents with diabetes.
Insulin pump therapy is recommended more and more to achieve and maintain optimal glycaemic control in patients with type 1 diabetes mellitus. The objective of our study was to evaluate the satisfaction of patients using insulin pump therapy and to determine its effectiveness in improving metabolic control in type 1 diabetic patients. This is a retrospective, descriptive and analytical study including 20 type 1 diabetic patients treated by insulin pump, between 2017 and 2021.
View Article and Find Full Text PDFPrevalence and Specific Manifestations of Non-alcoholic Fatty Liver Disease (NAFLD) and Diabetes Mellitus Type 2 Association in a Moroccan Population: A Cross-sectional Study.
Rev Diabet Stud
September 2022
Article Synopsis
- Non-alcoholic fatty liver disease (NAFLD) is a widespread condition linked to chronic liver disease, especially in people with type 2 diabetes mellitus (T2DM), increasing the risk of serious health complications.
- A study assessed 180 T2DM patients without alcohol or other liver issues, finding NAFLD present in 45.6% of them, with notable fibrosis in 18.3% of cases.
- NAFLD was significantly associated with conditions like obesity, metabolic syndrome, and hypertension, highlighting its potential to worsen health and increase cardiovascular risks in T2DM patients.*
Objectives: We present the first cases of two male brothers with Leydig cell hypoplasia secondary to a novel mutation in the LHCGR gene that has never been described before.
Case Presentation: We report the case of two brothers with Leydig cell hypoplasia (LCH) type II caused by novel homozygous inactivating mutation of the LHCGR gene, located in exon 10 in c 947 position. The two patients presented at 11 years 7 months and 1 year 6 months, respectively, with abnormal sexual development, micropenis and cryptorchidism.
Introduction: Insular thyroid carcinoma (ITC) was defined as a rare malignant thyroid cancer standing in an intermediate position between the well-differentiated (papillary and follicular) and the anaplastic thyroid carcinomas. The incidence was estimated around <1% and 10% worldwide. Despite its rarity, it remains the main cause of death from non-anaplastic follicular cell-derived thyroid cancers.
View Article and Find Full Text PDFBackground: Long-term glucocorticoid (GC) use is the most frequent cause of adrenal insufficiency through suppression of the hypothalamic-pituitary-adrenal axis. There are no guidelines for predicting adrenal insufficiency (AI) and minimizing its risk.
Methods: This is a prospective observational study carried out in the Endocrinology-Diabetology and Nutrition department between 2014 and 2021.
Article Synopsis
- Congenital adrenal hyperplasia (CAH) is a genetic disorder caused by 21-hydroxylase deficiency, which presents at birth and leads to both hormonal and physical changes.
- A case study of a 16-year-old girl showed typical symptoms of CAH, including lack of menstruation, underdeveloped breasts, and male-like characteristics, confirmed through imaging and hormone tests.
- Managing CAH in adolescents involves hormonal treatment and possibly surgery, highlighting the importance of early diagnosis and comprehensive care for sexual development anomalies.
Article Synopsis
- Teratomas are germ cell tumors that typically occur in the gonads, with rare cases found in the adrenal glands, especially in younger patients.
- A 56-year-old woman with abdominal pain was diagnosed with a large right adrenal teratoma through imaging and underwent successful surgical removal.
- Adrenal teratomas are often asymptomatic and are usually treated with surgery, which has a good prognosis, although more research is needed to fully understand their characteristics and development.
Article Synopsis
- This study is the first in Morocco to examine growth disorders among children in different school types (public, private, urban, rural) within Oujda-Angad Province.
- It involved a sample of 1,582 primary school students, revealing significant disparities in growth issues: public and rural schools had higher rates of short stature and underweight, while urban private schools had more cases of obesity.
- The findings emphasize the need for monitoring children's nutritional status and implementing strategies to address these growth disorders effectively.
Introduction: flexible insulin therapy (FIT) is considered as a crucial turning point in the management of type 1 diabetes. The purpose of this study was to evaluate the impact of this optimum therapeutic approach on improving metabolic control and decreasing hypoglycemic events in patients with type 1 diabetes.
Methods: thirty-seven type 1 diabetic patients were included in a five days training programme of FIT.
Pilomyxoid astrocytoma (PMA) is a freshly described figure of low-grade neoplasms encountered in early childhood. Nevertheless, its precise classification by the World Health Organization (WHO) is still debatable. Making an exact diagnosis relies on histological and immunohistochemical pathognomonic features with specific radiological findings.
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