Synopsis of recent research by authors named "Siguo Feng"
- Siguo Feng's recent research primarily focuses on the roles of macrophages in diabetic vasculopathy and ocular vascular diseases, highlighting how metabolic dysfunction and m6A modifications contribute to inflammation and macrophage polarization in these conditions.
- The studies employ advanced proteomics techniques, notably the Olink platform, to identify novel biomarkers in ocular diseases such as glaucoma and wet age-related macular degeneration (wAMD), suggesting a significant link between metabolism-related proteins and these conditions.
- Feng also investigates innovative therapeutic strategies, including novel multi-targeting kinase inhibitors for suppressing ocular neovascularization, addressing issues like drug resistance associated with current anti-VEGF treatments.