Publications by authors named "Sigridur Eliasdottir"

Article Synopsis
  • - SGLT2 inhibitors block transporters in the kidneys, which increases sodium and glucose excretion, leading to lower blood sugar levels, improved blood pressure, and weight loss.
  • - These medications have shown protective effects for the heart and kidneys, reducing the risk of cardiovascular death, hospitalization due to heart failure, and progression to advanced kidney disease.
  • - While SGLT2 inhibitors are generally safe and do not raise the risk of low blood sugar or acute kidney injury, they can lead to rare but serious side effects, like normoglycemic ketoacidosis and Fournier's gangrene, that require medical awareness.
View Article and Find Full Text PDF

Introduction: IgA nephropathy (IgAN) is the most common glomerulonephritis globally. Because of the heterogeneity of the disease prognostic biomarkers are highly needed.

Aim: To investigate associations between galactose-deficient IgA1 (Gd-IgA1) concentrations in plasma and urine and disease activity and progression in patients with IgAN.

View Article and Find Full Text PDF

Limited data exist on the comparison of blood pressure (BP) measurements using aneroid and oscillometric devices. The purpose of the study was to investigate the difference in BP obtained using oscillometric and aneroid BP monitors in 9- to 10-year-old children. A total of 979 children were divided into group O, which underwent two oscillometric BP readings followed by two aneroid readings, and group A, which had BP measured in the reverse order.

View Article and Find Full Text PDF

Background: Low birth weight has been associated with increased risk of hypertension later in life. The aim of this study was to evaluate the association between birth weight and blood pressure (BP) in healthy 9- to 10-year-old Icelandic children.

Methods: Each child underwent 4 seated BP measurements, and the BP percentile was calculated from the mean of the 4 measurements.

View Article and Find Full Text PDF

A large body of literature suggests an inverse relationship between birth weight and blood pressure in children, adolescents and adults. The most persistent findings have been observed in children with a history of low birth weight or intrauterine growth restriction, while a large number of studies carried out in populations with normally distributed birth weight have shown conflicting results. A recently reported strong direct association between high birth weight and blood pressure, and the significant positive effect of postnatal growth on blood pressure suggests that the fetal origins of adult disease hypothesis should be expanded to include the role of excessive fetal and postnatal growth.

View Article and Find Full Text PDF

The purpose of the study was to investigate blood pressure (BP) distribution, prevalence of hypertension, and correlation between BP and body mass index (BMI) in 9- to 10-year-old Icelandic children. Two manual and two automated BP measurements were performed in 1071 Icelandic children. Children with elevated BP underwent a second BP screening, and a third screening was performed if the BP was elevated at the second visit.

View Article and Find Full Text PDF