Publications by authors named "Signe Dolmer"

Article Synopsis
  • The study aimed to compare the effects of tapering off antipsychotic medication versus continuing it in patients with first-episode schizophrenia who were in remission from psychotic symptoms.
  • Due to difficulties in recruitment, only 29 participants were included, revealing poor adherence to maintenance treatment, with a slight advantage in symptom remission for those who tapered off medication.
  • The trial was ultimately inconclusive because of recruitment issues, highlighting the need for better study designs to understand the impact of maintaining versus discontinuing antipsychotic treatment in this patient population.
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Mental healthcare providers face many difficult interactions with patients that can be emotionally demanding and have adverse effects on their well-being. Recent theoretical models suggest that the interpretation of stressful episodes may be more important for psychological adjustment than the nature of the episodes. This study examined whether care providers' interpretations of mechanical restraint episodes were related to their adjustment.

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Background: The aim of the TAILOR trial is to investigate the effect of closely monitored tapering/discontinuation versus maintenance therapy with antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder and with minimum 3 months' remission of psychotic symptoms.

Methods And Design: Two hundred and fifty patients will be included from the psychiatric early intervention program, OPUS, in two regions in Denmark. Inclusion criteria are: ICD-10 diagnoses schizophrenia (F20, except F20.

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