Comparing Two Peanut Desensitization Protocols in Preschool Children: A Real-World Clinical Practice.

Introduction: Peanut allergy is the main food allergy in childhood and poses significant health concerns. This study aimed to critically evaluate the effectiveness and safety of oral immune therapy (OIT) using crushed peanuts versus peanut puffs.

Methods: Children with an allergist diagnosed peanut allergy based on a history of an IgE-mediated reaction and a positive skin prick test for peanuts were recruited at the Montreal Children's Hospital and the Children's Clinic located in Montreal.

Type Vb Double Common Bile Duct: A Rare Case Associated With Cholangiocarcinoma.

Double common bile duct (DCBD), also called extrahepatic biliary duct duplication, is a rare anatomical variation of the biliary anatomy that involves either the presence of a septum within the common bile duct (CBD) or an accessory CBD. The first case of DCBD was reported by Vesarius in 1543. A classification system for DCBD that included five types was proposed in 2007.

Primary Yolk Sac Tumor of the Liver: A Rare Cause of Bile Duct Obstruction.

Primary yolk sac tumor (YST) of the liver is an extremely rare extragonadal germ cell tumor. Here, we present a case of a young man who developed primary YST of the liver which metastasized to periductal lymph nodes causing bile duct obstruction. A 32-year-old male was referred from an outside hospital for evaluation of painless jaundice.

Electoral College bias and the 2020 presidential election.

Donald Trump's 2016 win despite failing to carry the popular vote has raised concern that 2020 would also see a mismatch between the winner of the popular vote and the winner of the Electoral College. This paper shows how to forecast the electoral vote in 2020 taking into account the unknown popular vote and the configuration of state voting in 2016. We note that 2016 was a statistical outlier.

Intravenous immunoglobulin inhibits IgE production in human B lymphocytes.

Background: Intravenous immunoglobulin (IVIG) is commonly used as both an immune-enhancing and immune-modulating agent. Treatment with high doses of IVIG diminishes IgE secretion in patients with severe steroid-dependent asthma.

Objective: We studied the action of IVIG on IgE production in highly purified B lymphocytes stimulated without additional T cells to determine the action of IVIG on B lymphocytes.

Immunotherapy for childhood asthma: is there a rationale for its use?

Objective: This paper reviews the literature regarding immunotherapy in the management of childhood asthma. Immunotherapy is a well established treatment of venom allergy and allergic rhinitis, however its use in asthma remains controversial.

Data Sources: We reviewed the pediatric literature from 1966 to 1994 and evaluated the existing studies for clinical efficacy of immunotherapy in childhood asthma.

Case report: milk-alkali syndrome and pancreatitis.

The relation between hypercalcemia and pancreatitis, first described in patients with hyperparathyroidism, is controversial. Other causes of hypercalcemia also have been associated with pancreatitis. In this report, the authors describe a patient with pancreatitis and the milk-alkali syndrome who had the classic triad of hypercalcemia, alkalosis, and renal insufficiency.

Laparoscopic cholecystectomy: a treatment option for gallbladder disease in children.

Laparoscopic cholecystectomy was performed safely in two children ages 7 and 15 years. Special considerations were required in the younger child because of the discrepancy between the length of the instruments and the size of the peritoneal cavity. Both children remained in hospital less than 24 hours and were able to resume normal diet and activity quickly.