Publications by authors named "Sigala Julien"
Article Synopsis
- The study aimed to create a simplified technique called the pre-IMSI test (PIT) to evaluate sperm morphology in infertile men, particularly those with normal or subnormal sperm, after multiple unsuccessful fertility treatments.
- Researchers selected 248 patients and categorized them into three subgroups based on their PIT scores, which measured the quality of motile sperm.
- Results showed that higher PIT scores were associated with better clinical pregnancy outcomes in ICSI procedures, highlighting the potential of the PIT as a predictive tool for ART success.
Article Synopsis
- The study compares serum progesterone levels on transfer day among three methods of endometrial preparation for frozen embryo transfer (FET): spontaneous cycles, ovarian stimulation cycles, and artificial cycles.
- Results showed that the ovarian stimulation group had significantly higher progesterone levels (29.47 ng/ml) compared to spontaneous (20.03 ng/ml) and artificial cycles (14.32 ng/ml), indicating a possible link to treatment methods.
- Despite differences in progesterone levels, demographic factors and overall pregnancy outcomes (live birth rates and pregnancy loss rates) were largely similar across all three groups, suggesting further research is needed to assess the clinical implications of progesterone variations.
Background: The limitations of conventional sperm analyses have highlighted the need for additional means of evaluating sperm quality.
Methods: In a study of a cohort of 245 men with known conventional sperm parameters, one-dimensional PAGE was used to monitor protein content and quality in samples from individual ejaculates.
Results: The sperm protein content varied markedly from sample to another, especially in the high-molecular-weight range.
A lower number of metaphase II oocytes eligible for vitrification after controlled stimulation in cancer patients has recently been reported, suggesting that cancer may impair the dynamics and quality of follicular growth. In this prospective, non-interventional study, the pattern of follicular growth and oocyte cohort after ovarian stimulation in cancer patients was analysed. Ninety cancer patients, recruited before starting chemotherapy, were compared with 180 time- and age-matched healthy controls undergoing intracytoplasmic sperm injection.
View Article and Find Full Text PDFObjective: Although an inhibin B assay may be useful in the assessment of testicular function in a number of genital conditions, reliable reference ranges are still lacking. The present study sought to establish the reference range for serum inhibin B by applying the updated Gen II assay.
Design: This prospective study included 818 men referred for semen analysis: 377 were normozoospermic (reference group) and 441 presented at least one abnormal semen parameter (case group).
Article Synopsis
- The study aimed to examine how polycystic ovarian morphology (PCOM) affects oocyte quality in women undergoing IVF-ICSI for male infertility.
- It involved 194 women split into PCOM and control groups, measuring oocyte maturation and abnormalities from both groups.
- Results showed that while PCOM patients had more oocytes and embryos, the quality of embryos was similar to controls, indicating that PCOM doesn't harm oocyte or embryo quality in IVF-ICSI.