Gilbert syndrome in patients with type 1 diabetes-Prevalence, glycemic control, and microalbuminuria.

Background: Gilbert syndrome (GS) is a common hereditary condition, characterized by intermittent unconjugated hyperbilirubinemia. In adults with type 2 diabetes and GS, a markedly lower prevalence of nephropathy was documented, suggesting a beneficial effect of hyperbilirubinemia. We investigated the prevalence of GS among individuals with type 1 diabetes mellitus (T1DM), and the prevalence of microalbuminuria.

Adiponectin levels in adolescent girls with polycystic ovary syndrome (PCOS).

Objective: To determine serum adiponectin concentrations in adolescent girls with and without polycystic ovary syndrome (PCOS) and to assess possible correlations of adiponectin levels with insulin and androgen levels.

Design: Prospective case-control study.

Setting: Endocrine clinics in the community.

Clinical and laboratory characteristics of adolescents with both polycystic ovary disease and anorexia nervosa.

In girls evaluated for anorexia nervosa (AN), coexistence of polycystic ovary disease (PCOS) was found when menstrual irregularities existed before weight loss, cessation of menses occurred at a relatively elevated body mass index, and LH and estrogen levels were elevated compared with adolescents with AN alone. In adolescents with PCOS + AN weight gain beyond recommended weight should not be advised.