Metabolomic analysis of HUVEC after Thermal denaturation UHPLC-MS/MS-based metabolomics.

Preserving denatured dermis has been shown to promote wound healing and improve skin appearance and function. Angiogenesis is crucial for the healing of burn wounds. However, the metabolic mechanisms underlying angiogenesis during burn recovery remain unclear.

Comparing the potential of benchtop and handheld mid-infrared spectrometers for predicting soil phosphorus (P) sorption capacity and evaluating the influence of sample preparation.

Traditional soil phosphorus (P) sorption capacity is examined from a Langmuir isotherm batch technique, which is time-consuming, labour intensive and generates chemical waste. In this work, we provide an efficient and convenient technique with MIR spectroscopy to predict the Langmuir parameter of soil P sorption maximum capacity (Smax, mg·kg). Four spectral libraries from benchtop (Bruker) and handheld (Agilent) MIR spectrometers were built with samples in two particle size ranges, <0.

Design of High-Entropy Tape Electrolytes for Compression-Free Solid-State Batteries.

Advanced solid electrolytes with strong adhesion to other components are the key for the successes of solid-state batteries. Unfortunately, traditional solid electrolytes have to work under high compression to maintain the contact inside owing to their poor adhesion. Here, a concept of high-entropy tape electrolyte (HETE) is proposed to simultaneously achieve tape-like adhesion, liquid-like ion conduction, and separator-like mechanical properties.

Severe Burn Injury Significantly Alters the Gene Expression and m6A Methylation Tagging of mRNAs and lncRNAs in Human Skin.

N6-methyladenosine (m6A) modulates RNA metabolism and functions in cell differentiation, tissue development, and immune response. After acute burns, skin wounds are highly susceptible to infection and poor healing. However, our understanding of the effect of burn injuries on m6A methylation and their potential mechanism is still limited.

Research trends on endoscopic mucosal resection: A bibliometric analysis from 1991 to 2021.

Background: In recent years, the rapid development of digestive endoscopy technology has brought revolutionary changes to endoscopic therapy. A growing number of articles have been published annually. We aimed to explore global scientific outputs and hotspots of endoscopic mucosal resection (EMR) published by different countries, organizations, and authors.

The Reliability and Reproducibility of a New Revised Edelson Classification.

Objective: Edelson classification is a 3D classification of proximal humeral fractures, but there is a scarcity of application of this classification in large samples, and the accuracy of classification was also not testified. The objective of this research was to verify whether a revised Edelson classification produces satisfactory agreement for proximal humeral fracture classification in adult patients.

Methods: A total of 827 proximal humeral fractures (304 male and 520 female patients, 58.

HSF-1: Guardian of the Proteome Through Integration of Longevity Signals to the Proteostatic Network.

Discoveries made in the nematode revealed that aging is under genetic control. Since these transformative initial studies, has become a premier model system for aging research. Critically, the genes, pathways, and processes that have fundamental roles in organismal aging are deeply conserved throughout evolution.

Insecticidal Triterpenes in Meliaceae: Plant Species, Molecules and Activities: Part Ⅰ (-).

Plant-originated triterpenes are important insecticidal molecules. The research on insecticidal activity of molecules from Meliaceae plants has always received attention due to the molecules from this family showing a variety of insecticidal activities with diverse mechanisms of action. In this paper, we discuss 102 triterpenoid molecules with insecticidal activity of plants of eight genera (, , , , , , , and ) in Meliaceae.

Comparison of total patellectomy and osteosynthesis with tension band wiring in patients with highly comminuted patella fractures: a 10-20-year follow-up study.

Background: The purpose of this study was to evaluate and compare the long-term clinical outcomes between the total patellectomy and osteosynthesis with tension band wiring in patients with highly comminuted patella fractures.

Methods: Between January 1987 and December 2003, this retrospective study included a total of 35 patients (mean age, 51.4±16.

Long-term outcomes after partial patellectomy in comminuted fractures - a clinical study.

Purpose: The purpose of this study was to evaluate the long-term clinical and radiographic outcomes of partial patellectomy (PP) in patients with patella comminuted distal pole fractures.

Methods: Seventeen patients who were diagnosed with patella comminuted distal pole fractures and underwent PP procedures were retrospectively included between January 1995 and January 2005. We collected patient demographics and data on the mechanism of injury, time to surgery, fracture type, follow-up time, and post-operative complications (infection, patellofemoral arthritis, and stiffness).

Associations Between Periosteal Reaction of Proximal Tibial and Medial Compartment Knee Osteoarthritis.

Objective: To evaluate and analyze the potential relationship between periosteal reaction and medial compartment knee osteoarthritis (KOA), and to assess the independent risk factors for the development of periosteal reaction associated with medial compartment KOA.

Methods: This is a retrospective comparative study. From January 2019 to December 2019 at the Third Hospital of Hebei Medical University, a total of 363 patients (726 knees) with medial compartment KOA were enrolled in this study according to our inclusion and exclusion criteria, including 91 males and 272 females, with an mean age of 57.

Comparison of outcomes of ORIF versus bidirectional tractor and arthroscopically assisted CRIF in the treatment of lateral tibial plateau fractures: a retrospective cohort study.

Background: Lateral tibial plateau fractures (TPFs) are often treated with conventional open reduction and internal fixation (ORIF) through standard anterolateral sub-meniscal arthrotomy. There has been increasing support for "bidirectional rapid redactor" device-assisted closed reduction and internal fixation (CRIF) for treating TPFs. The aim of the present study is to compare the clinical and radiological outcomes between CRIF and ORIF procedures.

Laboratory bioassay, greenhouse experiment and 3D-QSAR studies on berberine analogues: a search for new herbicides based on natural products.

Background: Berberine is a herbicidal chemical that we isolated from Coptis chinensis. In continuation of our program aimed at discovering and developing natural botanical herbicides, we evaluated the herbicidal activities of 39 berberine analogues and developed a three-dimensional quantitative structure-activity relationship (3D-QSAR) model.

Results: Among these 39 analogs, the most active compounds were determined to be worenine chloride and coptisine chloride, with median inhibitory concentration (IC ) values on all eight tested weed species of < 10 mg L .

An Axon-Pathfinding Mechanism Preserves Epithelial Tissue Integrity.

Epithelial tissues form the boundaries of organs, where they perform a range of functions, including secretion, absorption, and protection. These tissues are commonly composed of discrete cell layers-sheets of cells that are one-cell thick. In multiple systems examined, epithelial cells round up and move in the apical direction before dividing, likely in response to neighbor-cell crowding [1-6].

Chemical Composition, Algicidal, Antimicrobial, and Antioxidant Activities of the Essential Oils of Gaussen.

) Gaussen is a precious wood in the family Taxodiaceae. This study investigated the chemical components of the essential oil from the stem bark of and its algicidal, antifungal, and antioxidant properties. Sixty-nine compounds representing 89.

An efficient flexible graphene-based light-emitting device.

In recent years, flexible light-emitting devices (LEDs) have become the main focus in the field of display technology. Graphene, a two-dimensional layered material, has attracted great interest in LEDs due to its excellent properties. However, there are many problems such as efficiency, lifetime, and flexibility not well solved.

Development of a portable setup using a miniaturized and high precision colorimeter for the estimation of phosphate in natural water.

In this work, a high integrated water detection system comprised a miniaturized and high precision homemade colorimeter, a microfluidic analysis module and a wireless module was reported. A reagent reaction based on the ammonium molybdate spectrophotometric method was recorded for the estimation of phosphate in natural water. A laser self-modulating module of 880 nm was used as the radiation source.

A Miniaturized Colorimeter with a Novel Design and High Precision for Photometric Detection.

Water quality detection plays an increasingly important role in environmental protection. In this work, a novel colorimeter based on the Beer-Lambert law was designed for chemical element detection in water with high precision and miniaturized structure. As an example, the colorimeter can detect phosphorus, which was accomplished in this article to evaluate the performance.

Complete mitochondrial genome and phylogenetic analysis of (Cypriniformes: Cyprinidae).

is a freshwater cyprinid fish of high nutritional value, endemic to Shilin County, Southwestern China. In this study, we first sequenced the complete mitochondrial genome (mitogenome) of . The whole length of mitogenome is 16,585 bp, which contains 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes, and a control region.