Epigenetic state and expression of imprinted genes in umbilical cord correlates with growth parameters in human pregnancy.

Background: Genomic imprinting is a process causing genes to be expressed according to parental origin. Imprinting acts to coordinate fetal and prenatal growth, as well as control postnatal adaptations. Studies on human imprinting are confounded by tissue availability, sampling variability and limitations posed by tissue-specific expression and cellular heterogeneity within tissues.

The relationship between adrenomedullin, metabolic factors, and vascular function in individuals with type 2 diabetes.

Objective: Subjects with type 2 diabetes are at risk for vascular injury. Several vasoactive factors (e.g.