Publications by authors named "Siegfried Ertl"
Background/aims: To search for changes in body composition and energy metabolism associated with the repeatedly observed weight gain of cirrhotic patients after portosystemic shunting.
Methods: Twenty-one patients were studied prospectively before and 6 and 12 months after transjugular intrahepatic portosystemic shunt (TIPS) to assess body cell mass by two independent methods (total body potassium counting: body cell mass determined by TBP, BCMTBP, bioelectric impedance analysis: body cell mass determined by BIA, BCMBIA), muscle mass (anthropometry), resting energy expenditure (REECALO) by indirect calorimetry, and nutritional intake by dietary recall analysis.
Results: Prior to TIPS patients were hypermetabolic in terms of measured vs.
Loss of body cell mass in Cushing's syndrome: effect of treatment.
J Clin Endocrinol Metab
March 2002
Article Synopsis
- Cushing's syndrome (CS) is linked to low fat-free mass and a significant loss of body cell mass (BCM) and whole body protein, as demonstrated through various body composition assessment methods in a study involving patients with untreated CS.
- Patients with CS had higher body weight and fat compared to nonobese controls, but their total body potassium (TBP) levels indicated substantial BCM loss, with lower arm muscle area suggesting protein deficiency.
- Following pituitary surgery, while patients lost body weight and fat significantly, BCM and muscle mass did not improve, indicating that even after treatment for hypercortisolism, protein loss persists despite reductions in fat.