Publications by authors named "Sidra Saeed"

The key objective of the research was to investigate the potential of Hydrocotyle umbellata L. as a hyperaccumulator in copper (Cu)-contaminated environments and to enhance the understanding of its phytoextraction efficiency through the application of unsupervised machine learning techniques alongside statistical comparisons. The effects of Cu toxicity on pigment content, total flavonoids, total phenolic content, electrolyte leakage, translocation, and bio-concentration factors were analyzed in H.

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The effect of nutrition in the development and prognosis of cancer has received a lot of attention. Research shows taking vitamins, which are powerful antioxidants, can significantly lower the risk of cancers. Nutritional supplements suited to a patient's background, genetics, diet, tumour histology, and therapy may be beneficial in some cases.

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Introduction: Amid coronavirus disease 2019 (COVID-19) pandemic, accurate detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for diagnosis management and breaking down transmission chains. We designed a national external quality assessment panel (EQAP) for SARS-CoV-2 molecular detection comprising working laboratories nationwide.

Methods: A molecular diagnostic EQA panel that consists of five samples for SARS CoV-2 testing was distributed to 141 public and private sector laboratories across country.

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During the COVID-19 pandemic, concerns were raised that face covering use may elicit risk compensation; a false sense of security resulting in reduced adherence to other protective behaviours such as physical distancing. This systematic review aimed to investigate the effect of face covering use on adherence to other COVID-19 related protective behaviours. Medline, Embase, PsychInfo, EmCare, medRxiv preprints, Research Square and WHO COVID-19 Research Database were searched for all primary research studies published from 1st January 2020 to 17th May 2022 that investigated the effect of face covering use on adherence to other protective behaviours in public settings during the COVID-19 pandemic.

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Introduction: Influenza A viruses cause global health concerns due to their high amino acid substitution rates. They are linked to yearly seasonal epidemics and occasional pandemics. This study focused on sequencing influenza A virus strains in Pakistan.

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Cadmium (Cd) is the most toxic element which may cause serious consequences to microbial communities, animals, and plants. The use of green technologies like phytoremediation employs plants with high biomass and metal tolerance to extract toxic metals from their rooting zones. In the present work, was exposed to five Cd concentrations (2, 4, 6, 8, and 10 µmol) in triplicates to judge its phytoextraction ability.

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Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and prevention. One of the most significant advancements in modern oncology is the shift from an organ-centric strategy to a personalized strategy guided by deep molecular analysis. This shift in view, which focuses on the tumour's precise molecular changes, has paved the way for individualized treatment.

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Vegetable waste (spinach, potato, and cauliflower) is a rich and natural source of nutrients, potentially good for supplying minerals, essential amino acids, and antioxidants to the birds. Relatively, its cost very low, easily to accessible, easily process & pose little risk of illness. The aim of present study was to evaluate the effect of vegetable waste (VW) as feed supplement on growth performance and hematology of broiler chicks.

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Objective: We examined whether varying information about long COVID would affect expectations about the illness.

Method: In October 2021, we conducted a 2 (Illness Description: long COVID vs. ongoing COVID-19 recovery) × 2 (Symptom Uncertainty: uncertainty emphasized vs.

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Introduction: Collective evidence on risk factors for dental caries remains elusive in low- and middle-income countries (LMICs). The objective was to conduct a systematic review and meta-analysis on risk factors for dental caries in deciduous or permanent teeth in LMICs. Methods: Studies were identified electronically through databases, including Cochrane Oral Health Group Trials Register, Cochrane Central Register of Controlled Trials, PubMed/MEDLINE, and CINAHL, using “prevalence, dental caries, child, family, socioeconomic, and LMIC” as the keywords.

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Aroma is one of the key food characteristics determining consumers' perception and acceptability of products. L. is an aromatic herb commonly used as a food additive and taste enhancer.

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Article Synopsis
  • TNFα and NF-kB are key players in inflammation and complications related to coronary artery diseases (CAD), and the study explores the effects of nanoparticles (Au, ZnO, MgO) as potential anti-inflammatory treatments.
  • The researchers found that different nanoparticles effectively reduced TNFα and NF-kB levels in various types of CAD, with Au and MgO showing optimal therapeutic concentrations of 5 µg/ml, while ZnO was effective at 1 µg/ml, especially in certain disease categories.
  • Overall, the study suggests that these nanoparticles could serve as alternative anti-inflammatory agents in treating CAD and possibly other diseases, based on their ability to lower pro-inflammatory markers with minimal toxicity.
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Purpose: antibiotic resistant infections in high-risk patients are a great challenge for researchers and clinicians worldwide. In an effort to achieve potent bactericidal outcomes, a novel chitosan-mastoparan nanoconstruct (Mast-Cs NC) was designed and assessed for its therapeutic potential through in silico, in vitro and in vivo experimentation against clinical multidrug-resistant (MDR) .

Methods: Optimized 3D structures of mastoparan and chitosan were coupled computationally through an ionic cross-linker to generate a circular ring of chitosan encasing mastoparan.

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Background: Women in Pakistan lack appropriate awareness about diagnosis and treatment for breast cancer due to a range of multifaceted barriers. There is a dearth of literature examining the socio-cultural factors that inhibit women from breast cancer screening, diagnosis and treatment in Punjab, Pakistan. Addressing this gap, this qualitative study sought to identify and explore the barriers that hinder women from seeking timely screening and treatment.

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Background: Although polymethylmethacrylate (PMMA)-collagen gel is approved for correction of nasolabial folds, there are no reports characterizing safety and efficacy in the midface, an area where fillers are often used in clinical practice.

Objective: To determine the safety and efficacy of PMMA-collagen gel for long-term volume restoration in the midface.

Methods: In this prospective, single-center, 12-month study, 23 subjects with a pretreatment Midface Volume Deficit Scale (MFVDS) grade of 3, 4, or 5 were treated with PMMA-collagen gel.

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Article Synopsis
  • Microsponge is a cross-linked particle system that can absorb drugs, similar to a sponge, and can be prepared using different methods.
  • In this study, we utilized a quasi emulsion-solvent diffusion method, combining hydrophobic and hydrophilic polymers along with surfactants like Tween 80 and polyvinyl alcohol to create the formulations.
  • Our findings demonstrate, for the first time, the successful and optimized formulation of microsponge with ketoprofen, exhibiting the desired pharmaceutical properties.
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