Publications by authors named "Siddinath Gyawali"
Hypersensitivity to aspirin is rare disorder occurring in 1.88% of the patients. Aspirin-hypersensitive patients requiring single antiplatelet agent may be treated with clopidogrel, an alternative antiplatelet agent.
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- - Hepatocellular carcinoma, the most prevalent primary liver cancer, is commonly caused by factors like viral hepatitis, alcohol abuse, and autoimmune hepatitis, but often diagnosed at advanced stages, limiting curative options.
- - A study conducted from March 2020 to August 2022 at a tertiary care center found that 3.75% of 1440 patients with chronic liver disease had hepatocellular carcinoma, with most patients presenting with symptoms.
- - The majority of symptomatic patients had a history of alcohol consumption (68.52%) and smoking (74.07%), indicating that alcohol-related liver cirrhosis is a significant risk factor in this population.
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- A study in Wuhan focused on the psychological effects of COVID-19, revealing heightened levels of anxiety and depression among hospitalized patients.
- Conducted from July to August 2021, the research involved 360 patients and utilized questionnaires to assess mental health alongside demographic data.
- Findings showed that 44.7% of participants experienced anxiety, and 70.3% faced depression, indicating a significant prevalence of mental distress compared to the general population.
Article Synopsis
- - Patients with advanced cancer frequently experience sleep disorders such as insomnia and sleep apnea, which negatively affect their quality of life and may worsen cancer outcomes.
- - A study conducted in Nepal found that over 56% of 357 cancer patients had significant sleep disorders, with factors like gender and type of cancer influencing sleep quality.
- - The findings highlight the need for better sleep management strategies in cancer care to enhance patient quality of life and improve treatment outcomes.
Key Clinical Message: In babies presenting with an omphalocele, other components of the prune belly syndrome should be scrutinized for early diagnosis and timely intervention.
Abstract: A male baby on his 13th day of life presented with an omphalocele. On evaluation, he had congenital absence of left kidney and bilateral cryptorchidism.
Introduction: Breast cancer is one of the most common cancers worldwide both in terms of incidence and mortality. Its incidence has been on an increasing trend in developing nations including Nepal, however, there is very limited evidence of its demographic profile in our setting. This study aimed to find out the prevalence of breast cancer among cancer patients visiting the Department of Internal Medicine of a tertiary centre.
View Article and Find Full Text PDFKey Clinical Message: The pelvic and peritoneal hydatidosis occurs mostly after the traumatic rupture or surgical spillage of from liver or spleen. The treatment is surgical aiming to eradicate local disease, preventing complications, and reducing recurrences.
Abstract: We report a unique case of a 26-year-old male who presented with acute urinary retention and abdominal distention.
Key Clinical Message: Fetal bradycardia and congenital complete heart block could be the presentation of neonatal lupus. A high index of suspicion of this condition helps to identify an asymptomatic mother.
Abstract: Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease of newborns due to placental transfer of Ro/SSA or La/SSB autoantibodies.
Unlabelled: The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/or surgical interventions, the median survival of patients with adenosquamous carcinoma, one of the histological variants, is less than a year.
View Article and Find Full Text PDFAn 83-year-old-male patient presented with obstructive jaundice, whose imagings were consistent with the cholangiocarcinoma of the distal common bile duct. The tumor markers were within normal limits. IgG4 level was raised; therefore, IgG4-sclerosing cholangitis was made as the provisional diagnosis.
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