A Short Course of Preoperative Denosumab Injection Followed by Surgery in High-Risk Giant Cell Tumors of the Extremities: A Retrospective Study.

Despite early promising results with denosumab treatment in giant cell tumor of bone (GCTB), recent studies have raised concerns about a high local recurrence rate following preoperative denosumab administration and joint preservation surgery. This retrospective study evaluated data from 25 high-risk GCT patients (Campanacci grade II or III with features like soft tissue extension, pathological fracture, minimal periarticular or subarticular bone) treated with five doses of neoadjuvant denosumab injection followed by either curettage and cementing ( = 13) or joint reconstruction with fibular graft/endoprosthesis ( = 12) between 2014 and 2019. With an average follow-up of 40 months, the study found only one patient of local recurrence.

Aneurysmal Bone Cyst of the Distal Ulna in an Elderly Lady.

Introduction: Aneurysmal bone cyst (ABC) is a rare, benign, cystic, hemorrhagic expansile osteolytic lesion of unknown etiology resembling multiple intraosseous blood-filled spaces mostly seen in the first two decades of life. It accounts for <1% of all bone tumors and the usual sites are the metaphyses of the proximal and distal femur, proximal tibia, and posterior elements of the spine. Affection of other sites is unusual.

Intra-articular anterior inferior iliac spine avulsion with hip instability: A retrospective study.

Background: Intraarticular anteroinferior iliac spine (AIIS) avulsion fractures combined with hip dislocation are infrequently reported in medical literature. This study aims to present the outcomes of surgical treatment for this rare type of injury.

Methods: We retrospectively analyzed six cases of AIIS avulsion fracture with hip dislocation treated surgically.

Association between nutritional scores and multilevel vertebral involvement in tubercular spine: a retrospective cohort study.

Objective: The objective of this study is to evaluate the prognostic value of nutritional scores comprising the Controlling Nutritional Status (CONUT) score and the Prognostic Nutritional Index (PNI), in prediction of multilevel vertebral involvement (> 2 vertebra) in Spinal Tuberculosis (STB).

Methods: Retrospective analysis of 39 STB patients was conducted to assess nutritional indices (CONUT and PNI) and the numbers of vertebral affection. Spearman's correlation was used to examine the association between these variables.

Reconstruction of the extensor mechanism using polypropylene mesh in a displaced pathological fracture of the patella affected by giant cell tumour.

A man in his 30s came to our clinic with a year-long history of progressive pain and swelling in his knee. Diagnostic imaging revealed a displaced patellar fracture with an osteolytic, septated lesion and thinned expanded cortex in both fracture fragments. A core needle biopsy confirmed the diagnosis of giant cell tumour.

Integrative study of Permian coal-bearing horizons: biostratigraphy, palaeovegetation, and palaeoclimate in the South Karanpura Basin.

The article deals with the integrated and comprehensive study of the coal-bearing horizons from the South Karanpura Basin to delineate the biostratigraphy, palaeovegetation, palaeodepositional settings, and palaeoclimate in and around the investigated area during the deposition of Permian sediments. Highly diversified megafloral assemblages consist 13 genera and 72 species of order Glossopteridales, Cordaitales and Equisetales are documented among which 37 taxa are newly reported from Barakar and Raniganj formations of the area. Palynoassemblages-I and -II are recovered, which demonstrate the biostratigraphic age as Kungurian and Wordian-Capitanian, respectively.

Impact of limb length discrepancy on functional outcome in total knee arthroplasty patients: a prospective cohort study.

Background: Limb length alteration following total knee arthroplasty (TKA) has been under-reported. Few studies have shown a significant association between limb length discrepancy (LLD) and poor functional outcome. This prospective study evaluated the impact of radiographic and perceived LLD on functional outcome in TKA.

Limb length discrepancy after total knee arthroplasty: A systematic review and meta-analysis.

Background: Limb length discrepancy (LLD) after total knee arthroplasty (TKA) has been considered as one of the reasons for the unsatisfactory outcome. However, there is no consensus about the extent of LLD that can be considered as clinically relevant.

Aim: To evaluate the incidence of radiographic LLD and its impact on functional outcome following TKA.