Precision in Midst of Crisis: Rigid Bronchoscopy in Management of Intrapulmonary Hemorrhage.

Rarely we encountered massive intra-pulmonary hemorrhage in clinical practice, which is always considered a life-threatening condition. In this case report we will discuss its management with removing blood clots using a rigid bronchoscope. Moreover, we also discuss about innovation, using a flexible fibre-optic bronchoscope through the rigid bronchoscope and removing a huge blood clot from terminal bronchioles.

Evaluation of the effectiveness of novel oral hygiene aids in the prevention of gingival diseases in children and adolescents with special healthcare needs - A systematic review and meta-analysis.

Background: Due to a lack of manual dexterity, impaired cognitive and general development, and awareness of caregivers, special children are not able to maintain good oral health. This leads to the development of dental plaque, gingival inflammation, and further periodontal diseases. It is, thus, necessary for dentists and caregivers to understand which of oral hygiene aids can be best suited for a child with special healthcare needs.

Binaural auditory beats vs music of choice as audio distraction behaviour guidance technique among children: A randomized controlled trial.

Background: Binaural beat is created by presenting two different pure-tone sine waves with less than a 30Hz difference dichotically. In dental settings, children listening to familiar music during treatments gain control over the anxiety caused by tools like the airotor or syringe, creating a comforting, familiar environment.

Aim: To evaluate and compare anxiety level during restorative treatment using No Music, Music of choice and Binaural Auditory Beats as Audio distraction behaviour guidance technique in children aged 6-12 years.

Stabilizing Diketopyrrolopyrrole Radical Cations Through Carbazoles: Substitution Pattern vs Spin Delocalization.

The synthesis of organic radicals continues to garner significant interest due to their fascinating optical, electronic, and magnetic properties. Moreover, the growing demand for chemically stable organic radicals is driven by the rapid expansion of the market for electronic devices utilizing organic semiconductors. In this context, the development of multifaceted approaches for the design of stable organic radicals is of great importance.

Evaluation of stress generation in core build up-material of mutilated primary teeth: a comparative finite element analysis between BioFlx, stainless steel and zirconia crowns.

Stainless-steel crowns (SSCs) are the most durable restorative option for deciduous teeth, although they are unsightly. However, prefabricated zirconia crowns (ZCs) look more pleasant but require substantial dental preparation. Recently, BioFlx crowns have been introduced as a white-colored alternative to SSCs, providing both flexibility and aesthetics.

Antimicrobial Efficacy of , , and Chlorhexidine Mouthwashes on and in Children: A Comparative Study.

Background: Herbal medicines are both promotive and preventive in inhibiting dental caries. Most commonly used natural plant extracts like mango () and pudina () as an entire or together are scientifically well proven to be safe and effective against various oral health problems, especially in preventing dental caries and periodontal diseases.

Aim: The present study aims to comparatively evaluate the effect of , , and Chlorhexidine (CHX) (0.

Comparative Evaluation of Antibacterial Efficacy and Remineralization Potential of Acidulated Phosphate Fluoride Gel with Herbal Dental Gel Containing and An Study.

Aim: The aim of the study is to evaluate and compare the antibacterial efficacy and remineralization potential of acidulated phosphate fluoride (APF) gel with herbal dental gel containing and

Materials And Methods: Ethanolic extracts of and were prepared. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of these extracts were determined against and using the resazurin method and agar plate streaking method, respectively. The herbal dental gel was formulated, and its cytotoxicity was evaluated using an 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay.

Bioproduction, purification, partial characterization and phenol removal efficacy of tyrosinase enzyme from Streptomyces sp. strain MR28.

The study focused on the production of the tyrosinase enzyme from Streptomyces sp. MR28 and its potency in removal of phenol content from water using free and immobilized tyrosinase enzyme. The tyrosinase was produced by Streptomyces sp.

Primary Palliative Care in Urology: Quality Improvement Summit 2021-2022.

Introduction: The AUA convened a 2021-2022 Quality Improvement Summit to bring together interdisciplinary providers to inform the current state and to discuss potential strategies for integrating primary palliative care into urology practice. We hypothesized that the Summit findings would inform a scalable primary palliative care model for urology.

Methods: The 3-part summit reached a total of 160 interdisciplinary health care professionals.

Comparing the Biofilm Removal Capacity of NaOCl, Povidone-Iodine, Chlorhexidine, Curcumin, and Triphala as Endodontic Irrigants.

Background And Aim: A sessile multicellular organism that is immersed in a self-produced matrix of extracellular polymeric substances and has its cells firmly attached to a surface is referred to as a microbial biofilm. When it comes to pulp and periradicular pathosis, biofilms are crucial. To reduce the number of microorganisms in the root canal and assist in treating periapical pathosis, endodontic therapy must include decontamination of the system of tooth root canals through biomechanical preparation and irrigation of the root canal.

Evaluation of Presence of in Root Canals of Deciduous Molars with Necrotic Pulp by Agar Culture and Polymerase Chain Reaction.

Objective: To assess the presence of in root canals of deciduous molars with necrotic pulp by agar culture and polymerase chain reaction (PCR) assay.

Materials And Methods: This is an experimental study, where a total of 120 endodontic samples were taken from deciduous molars with necrotic pulps. The presence of was assessed by culture, using Enterococcus confirmatory agar, and by PCR assay.

investigation on the biological activities of squalene derived from the soil fungus .

The consistent increase in multidrug resistance among pathogens and increased cancer incidence are serious public health concerns and threaten humans by killing countless lives. In the present study, CJ15 was characterized and evaluated for its antibacterial, candidicidal and cytotoxic activities. The selected isolate CJ15 with 18S rRNA gene sequence of 1021 base pairs exhibited antifungal activity on plant pathogens via dual culture.

Efficacy of Strain AK-7 Derived Bioactive Metabolites on Antimicrobial, Antioxidant, and Anticancer Activity against Human Ovarian Teratocarcinoma (PA-1) Cell Line.

Natural metabolites from beneficial fungi were recognized for their potential to inhibit multidrug-resistant human and plant fungal pathogens. The present study describes the isolation, metabolite profiling, antibacterial, and antifungal, antioxidant, and anticancer activities of soil fungi. Among the 17 isolates, the AK-7 isolate was selected based on the primary screening.

Comparative evaluation of marginal adaptation of mineral trioxide aggregate, Biodentine, and geristore as a root end filling material: An scanning electron microscope study.

Aim: The aim of this study was to measure the quality of marginal adaptation of three root end filling materials by scanning electron microscope (SEM).

Methodology: Thirty extracted human permanent single-rooted single canal maxillary anterior teeth with mature apices were prepared up to 60 K-file and obturated. Teeth were resected 3 mm from the apex using a cross-cut fissure bur at 90° angle to the long axis of the tooth.

Risk Factors for Relapse in Nonseminomatous Testicular Cancer After Postchemotherapy Retroperitoneal Lymph Node Dissection With Viable Residual Cancer.

Purpose: No consensus exists on the management of men with nonseminoma and viable nonteratomatous germ cell tumor in the postchemotherapy retroperitoneal lymph node dissection (pcRPLND) specimen after first-line chemotherapy. We analyzed surveillance versus different adjuvant chemotherapy regimens and the influence of time to pcRPLND on oncologic outcomes.

Methods: Data on 117 men treated with cisplatin-based first-line chemotherapy between 1990 and 2018 were collected from 13 institutions.

Comparative evaluation of anxiety level during restorative treatment using no music, monaural beats, and binaural auditory beats as audio distraction behavior guidance technique in children aged 6-12 years: A randomized clinical trial.

Background: Binaural auditory beat is an auditory illusion perceived when two different pure-tone sine waves with less than a 30 Hz difference are presented to a listener dichotically. Monaural beat stimulation is achieved by the superposition of amplitude-modulated signals of nearby frequencies to both ears simultaneously.

Aim: The study aims to evaluate and compare anxiety level during restorative treatment using no music, monaural beats, and binaural auditory beats as audio distraction behavior guidance techniques in children aged 6-12 years.

Exploring the Antimicrobial, Anticancer, and Apoptosis Inducing Ability of Biofabricated Silver Nanoparticles Using Flower Buds against the Human Osteosarcoma (MG-63) Cell Line via Flow Cytometry.

Biosynthesized nano-composites, such as silver nanoparticles (AgNPs), can be engineered to function as smart nano-biomedicine platforms for the detection and management of diverse ailments, such as infectious diseases and cancer. This study determined the eco-friendly fabrication of silver nanoparticles using (L.) Pers.

Predicting Limited Survival Following Inguinal Lymph Node Dissection in Penile Cancer: Should We Revisit the Goals of Care?

Objective: Patients with advanced penile squamous cell cancer have a poor prognosis and can benefit from early palliative care consultation. We built a model to identify those patients most likely to benefit.

Methods: Patients with penile squamous cell cancer undergoing inguinal lymph node dissection were identified from the National Cancer Database (NCDB) and a multi-institutional international dataset (INT).

GC-MS Based Characterization, Antibacterial, Antifungal and Anti-Oncogenic Activity of Ethyl Acetate Extract of Strain AK-6 Isolated from Rhizospheric Soil.

Rhizospheric soil is the richest niche of different microbes that produce biologically active metabolites. The current study investigated the antimicrobial, antifungal and anticancer activities of ethyl acetate extract of the potent rhizospheric fungus AK6 (AK-6). A total of six fungal isolates were isolated, and isolate AK-6 was selected based on primary screening.

Exploring knowledge, perspectives, and misperceptions of palliative care: A mixed methods analysis.

Objectives: To better understand palliative care knowledge and beliefs of patients with stage II or greater bladder cancer and their caregivers.

Subjects And Methods: Participants were primarily patients diagnosed with muscle-invasive or locally advanced bladder cancer. All were encouraged to enroll with a caregiver (defined as the individual who most closely assists with a patient's care).

Analysis of Prescribing Practices in the Dermatology Outpatient Department of a Tertiary Care Teaching Hospital.

Introduction The practice of appropriately prescribing and delivering pharmaceuticals to the right patient for the diagnosis, prevention, and treatment of diseases is referred to as "rational drug usage". Patients should receive pharmaceuticals that are appropriate for their clinical needs, given in doses that meet their needs, for long enough periods of time, and for the least amount of money possible. Minimizing drug therapy costs without sacrificing therapeutic effectiveness, avoiding unnecessary adverse medication reactions and drug-drug interactions, and improving therapeutic care while encouraging patient adherence are the main objectives of rational drug usage.

Simulated drought stress unravels differential response and different mechanisms of drought tolerance in newly developed tropical field corn inbreds.

Corn is one of the most important cereal crops in the world with highest yield potential. Nevertheless, its potential productivity is constrained by the occurrences of drought stress worldwide. Besides, in the era of climate change, frequent occurrences of severe droughts are predicted.

An Evaluation of Retention and Antibacterial Efficacy of Posterior High Strength Glass Ionomer Cement and Glass Hybrid Bulk-fill Alkasite Restorative Material as Conservative Adhesive Restoration in Children with Mixed Dentition: A Comparative Study.

Aim: The aim of the study was to compare and evaluate the retention and antibacterial efficacy of posterior high strength glass ionomer cement and glass hybrid bulk-fill alkasite restorative material as a conservative adhesive restoration in children with mixed dentition.

Materials And Methods: A total of 60 children of age 6-12 years with mixed dentition were selected and divided into group I (control group = 30): posterior high strength glass ionomer cement and group II (experimental group = 30): glass hybrid bulk-fill alkasite restorative material. Restorative treatment was carried out using these two materials.

Palliative care knowledge, attitudes, and experiences amongst patients with bladder cancer and their caregivers.

Objectives: Palliative care is underutilized amongst patients with bladder cancer despite guideline recommendations and known benefits. In order to uncover potential access barriers, we sought to describe patient and caregiver knowledge, attitudes and experiences surrounding palliative care.

Methods: We surveyed 272 patients with bladder cancer and their caregivers through the Bladder Cancer Advocacy Network Patient Survey Network.