Publications by authors named "Siddaiah B M"
Article Synopsis
- Parkinson's disease (PD) is a progressive condition marked by the loss of dopamine-producing neurons, which leads to various movement difficulties and other symptoms.
- Pramipexole (PPX) is a drug used for PD treatment, but it has limitations such as a short half-life and side effects, prompting research into enhanced formulations like PPX-loaded nanoparticles.
- The study developed a new biodegradable nanoparticle complex (PPX-PVP-CuO NC) that significantly improved treatment outcomes in a PD model by enhancing behavior and reducing oxidative stress markers, suggesting it could be a promising therapeutic option for managing PD.
