Design of Core-Shell Structured Magnetic Microwire with Desirable Properties for Multifunctional Applications.

Amorphous Co-rich microwire with excellent soft magnetic and mechanical properties produced by melt-extraction technique are emerging as a multifunctional material for a variety of applications ranging from ultrasensitive magnetic field sensors to structural health self-monitoring composites. The residual stress of extraction process often degrades the mechanical characteristics and magnetic softness of as-quenched amorphous microwire. It is a pressing need for enhancing these properties to make the microwire practical for integration into new technologies.

Reconstruction of Ferromagnetic/Paramagnetic Cobalt-Based Electrocatalysts under Gradient Magnetic Fields for Enhanced Oxygen Evolution.

The rational manipulation of the surface reconstruction of catalysts is a key factor in achieving highly efficient water oxidation, but it is a challenge due to the complex reaction conditions. Herein, we introduce a novel in situ reconstruction strategy under a gradient magnetic field to form highly catalytically active species on the surface of ferromagnetic/paramagnetic CoFeO@CoBDC core-shell structure for electrochemical oxygen evolution reaction (OER). We demonstrate that the Kelvin force from the cores' local gradient magnetic field modulates the shells' surface reconstruction, leading to a higher proportion of Co as active sites.

Performance of Fluxgate Magnetometer with Cu-Doped CoFeSiB Amorphous Microwire Core.

In this study, we investigated the effects of Cu doping on the performance of CoFeSiB amorphous microwires as the core of a fluxgate magnetometer. The noise performance of fluxgate sensors primarily depends on the crystal structure of constituent materials. CoFeSiB amorphous microwires with varying Cu doping ratios were prepared using melt-extraction technology.

Thermal Expansion Behavior of Co-Spray Formed Al-20Si/7075 Bimetallic Gradient Alloy.

Bimetallic gradient alloys have attracted research attention recently due to their potential applications in the aerospace and automobile industries. In this study, Al-20Si/7075 bimetallic gradient alloys were successfully manufactured by co-spray forming and the roll process. We investigated the thermal expansion behavior of the gradient alloy.

Dataset on comparable magnetocaloric properties of melt-extracted GdTbCoAl metallic glass microwires.

The data in this article is the supplementary data of the research article entitled "Comparable magnetocaloric properties of melt-extracted GdTbCoAl metallic glass microwires" (Yin et al., 2020). The data shows the circular cross section of GdTbCoAl metallic glass microwires with a diameter of ∼55 μm.

Perlecan/Hspg2 deficiency impairs bone's calcium signaling and associated transcriptome in response to mechanical loading.

Perlecan, a heparan sulfate proteoglycan, acts as a mechanical sensor for bone to detect external loading. Deficiency of perlecan increases the risk of osteoporosis in patients with Schwartz-Jampel Syndrome (SJS) and attenuates loading-induced bone formation in perlecan deficient mice (Hypo). Considering that intracellular calcium [Ca] is an ubiquitous messenger controlling numerous cellular processes including mechanotransduction, we hypothesized that perlecan deficiency impairs bone's calcium signaling in response to loading.

Discontinued Drugs for the Treatment of Cardiovascular Disease from 2016 to 2018.

Cardiovascular drug research and development (R&D) has been in active state and continuously attracts attention from the pharmaceutical industry. However, only one individual drug can eventually reach the market from about the 10,000 compounds tested. It would be useful to learn from these failures when developing better strategies for the future.

Non-extended cryoablation could be a new strategy in lung cancer management: An experiment on green fluorescent protein-labeled Lewis lung cancer-bearing mice.

Modern cryoablation has been performed in solid tumor management for more than two decades. Following the surgical spirits, it seems natural to pursue radical procedures in clinical practice, which results in unnecessary adverse effects. The attempt to use non-extended procedure made some marked achievements in practice but was criticized severely, because it was supposed to induce residual tumors, which would trigger the rapid development of cancer.