Publications by authors named "Sicen Meng"
Background: Gout is a chronic inflammatory diseases caused by monosodium urate crystal deposition. However, the role of interleukin (IL)-36 in gout has not dbeen elucidated.
Methods: We enrolled 75 subjects, including 20 healthy controls (HC), 30 patients with acute gout attack and 25 patients in remission.
Background: Imbalances in cytokine networks have been shown to be a possible cause of rheumatoid arthritis (RA). The interleukin (IL)-12 family is involved in the pathogenesis of autoimmune diseases including RA, while IL-39 is a newly discovered member of the IL-12 family, although its role in RA remains unclear. The purpose of the present study was to detect the expression of IL-39 in the sera of patients with RA and its relationship with RA activity.
View Article and Find Full Text PDFPotential clinical value of serum interleukin-41 levels in patients with acute gout.
Int Immunopharmacol
September 2023
Article Synopsis
- Gout is a common disease, and this study aimed to understand the levels of interleukin-41 (IL-41) in gout patients, which had not been previously reported.
- The research involved 81 participants, including patients with acute gout, those in remission, and healthy controls, using blood tests to measure IL-41 levels and analyze correlations with other health parameters.
- Findings showed that IL-41 levels were significantly higher in acute gout patients compared to healthy controls and suggested that IL-41 could serve as a diagnostic marker for acute gout, especially when combined with uric acid levels.