Publications by authors named "Sibel Kaplan Sarikavak"
Background: Primary immune deficiencies (PID) encompasses genetic disorders that result in recurrent infections and immune dysregulation, often increasing the risk of malignancies. The aim of this study is to determine the quality of life, depression, and anxiety in parents of children with PID.
Methods: Various validated assessment tools, including the Beck Depression Inventory (BDI), State and Trait Anxiety Inventory (STAI), the 36-item Short Form Survey (SF-36), and a demographic form, were employed to gather data from 85 parents of 64 PID patients and 85 parents of 75 healthy children.
Article Synopsis
- Primary immune deficiencies (PIDs) are rare genetic disorders that result in weakened immune systems, leading to frequent infections and a higher risk of cancer and lymphoproliferative disorders.
- In a study of 550 pediatric patients with PID, 17 (3.0%) were found to have malignancies or benign lymphoproliferations, with immune dysregulatory diseases being the most common cause.
- Lymphoma was the most frequently observed malignancy, and Epstein-Barr virus was identified as the most common viral agent involved, emphasizing the need for early diagnosis and ongoing care for affected patients.