Publications by authors named "Sibei Liu"
Background: The prevalence of chronic respiratory diseases is increasing globally. There is evidence that those with spirometric impairment, and no signs of obstruction (termed preserved ratio impaired spirometry [PRISm]), have an increased risk of morbidity and mortality compared with those with normal lung function. Several gaps remain in characterizing PRISm.
View Article and Find Full Text PDFArticle Synopsis
- The subcortical maternal complex (SCMC) is crucial for early mammalian embryonic development, and mutations in its key components (NLRP5, TLE6, OOEP) are linked to reproductive issues.
- Recent research has revealed the cryogenic electron microscopy structure of the human SCMC, highlighting the importance of the NLRP5 pyrin domain for maintaining the complex's stability.
- The study introduces a new method to assess SCMC stability and identifies a new pathogenic variant in TLE6, providing a basis for diagnosing fertility disorders and discovering other infertility-related variants.
Objective: To evaluate sociodemographic and clinical factors associated with clinical outcomes in patients hospitalized with neuroinfectious diseases at three tertiary care centers in New York City.
Methods: This retrospective cohort study was conducted at three large urban tertiary care centers between January 1, 2010 and December 31, 2017. Poor clinical outcome was defined as length of hospital stay (LOS) ≥2 weeks and/or discharge to a location other than home.
Background: More than 90% of the morbidity and mortality from chronic respiratory disease occurs in low-income and middle-income countries (LMICs), with substantial economic impact. Preserved ratio impaired spirometry (PRISm) is a prevalent lung function abnormality associated with increased mortality in high-income countries. We aimed to conduct a post-hoc analysis of a cross-sectional study to assess the prevalence of, the risk factors for, and the impact of PRISm in three diverse LMIC settings.
View Article and Find Full Text PDFArticle Synopsis
- The subcortical maternal complex (SCMC) is super important for early development of embryos, and problems with it can cause reproductive issues in women.
- Scientists recreated the SCMC in mice and figured out its tiny structure using advanced imaging, finding out that it has key parts called MATER, TLE6, and FLOPED that work together.
- They discovered that changes in the SCMC linked to female reproductive diseases could help lead to better ways to diagnose and understand these conditions in women.
Article Synopsis
- Scientists have created a special reactor called PF-MBBfR to treat dirty water without needing air, using a mix of microalgae and bacteria.
- They found that specific conditions, like the right amount of organic material, helped the biofilm (a mix of algae and bacteria) grow better and clean the water more effectively.
- The research showed that the microalgae were really good at using nitrogen, which helped reduce pollution levels even more and used less energy in the process.
Background Childhood maltreatment (CM) significantly increases the risk of adulthood psychopathology. Interplay between susceptible genetic variations and CM contributes to the occurrence of depression. This review aims to systematically synthesize the relationships between genetic variations and depression among those exposed to CM.
View Article and Find Full Text PDFPurpose: To explore the mediating effect of school interest and maladaptive cognitions in the relationship between stress and Internet addiction.
Design And Methods: A total of 2271 high school students were recruited from a Chinese high school. Serial mediation model was used.
Background: Child maltreatment predicts a significant risk factor for depression. The relationship between child maltreatment and depression has been shown to vary as a function of genetic factors. There have been very few systematic reviews conducted to date to synthesize what DNA methylations and/ or genetic variations interact with childhood maltreatment in the course of depression.
View Article and Find Full Text PDF