Can elimination of epinephrine in rhinoplasty reduce the side effects: introduction of a new technique.

Background: We aim to provide evidence that despite not administering epinephrine, (1) the amount of hemorrhaging during surgery will not change, (2) surgery time will not increase and may even be shorter, and (3) there would be fewer cardiovascular-related consequences.

Methods: One hundred thirteen patients were enrolled and randomized into the control (n = 74) and intervention groups (n = 39). During the primary open or closed rhinoplasty operation, anesthesia was managed by continual infusion of remifentanil (14-20 μg/h) and propofol (4-6 mg/kg/h) with an infusion pump, in addition to N(2)O-O(2) (50%).