Multi-species alignments of intronic sequences and putative transcriptional regulators.

This data article contains multi-species alignments of the regulatory region of LIM-HOX gene and lists of transcription factors that are predicted to bind to enhancers and regulate expression in amphid neurons. For further details and experimental findings please refer to the article by Amon and Gupta in Developmental Biology (S. Amon, B.

Intron-specific patterns of divergence of lin-11 regulatory function in the C. elegans nervous system.

The diversity of neurons in the nervous system is specified by many genes, including those that encode transcription factors (TFs) and play crucial roles in coordinating gene transcription. To understand how the spatiotemporal expression of TF genes is regulated to generate neuronal diversity, we used one member of the LIM-Hox family, lin-11, as a model that is necessary for the differentiation of amphid neurons in the nematode C. elegans and a related species C.

A microfluidic phenotype analysis system reveals function of sensory and dopaminergic neuron signaling in C. elegans electrotactic swimming behavior.

The nematode (worm) C. elegans is a leading multicellular animal model to study neuronal-basis of behavior. Worms respond to a wide range of stimuli and exhibit characteristic movement patterns.