Translation, cross-cultural adaptation and validation of the Chinese version of supportive and palliative care indicators tool (SPICT-CH) to identify cancer patients with palliative care needs.

Introduction: People diagnosed with cancer are the most frequent users of palliative care. However, there are no specific standards for early identifying patients with palliative care needs in mainland China. The Supportive and Palliative Care Indicators tool (SPICT) can identify patients with cancer who are in need of palliative care across healthcare settings.

A bifunctional naphthalimide-based fluorescent probe for imaging lysosomal peroxynitrite and viscosity in living cells and zebrafish.

Peroxynitrite (ONOO) and viscosity are critical indicators of lysosome functionality, intimately linked to numerous diseases' pathophysiological processes. Hence, creating reliable analytical techniques to observe fluctuations in lysosomal ONOO and viscosity is highly important. This study presents the development of a novel naphthalimide-based fluorescent probe, Nap-Cy, specifically designed to target lysosomes and simultaneously detect both ONOO and viscosity.

Intimate partner violence and its associated psychosocial factors among women with breast and/or cervical cancer in China: A cross-sectional study.

Purpose: This study aimed to investigate the prevalence of intimate partner violence among women with breast cancer and/or cervical cancer in China and to explore its psychosocial associated factors.

Methods: From July to September 2023, we firstly conducted reliability and validity tests using the simplified Chinese version of the Women Abuse Screening Tool in 150 women with breast and/or cervical cancer. We then used a questionnaire comprising the Chinese version of the Women Abuse Screening Tool, Multidimensional Scale of Perceived Social Support, European Organization for Research and Treatment Quality of Life Questionnaire-Core 30, and Experiences in Close Relationships Inventory Scale in 401 women with breast and/or cervical cancer.

Interventions to enhance the core competencies of clinical nursing preceptors: A systematic review.

Unlabelled: Aim This systematic review aimed to identify intervention studies on core competencies of clinical nursing preceptors, evaluate their quality using quantitative indicators, and summarize the effectiveness of the intervention programs and limitations of included studies.

Design: This review was reported in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 checklist.

Data Sources: Between May 1, 2024 and May 30, 2024, we searched PubMed, Web of Science, CINAHL, Medline, EMBASE and ProQuest (Health & Medical Collection) to get relevant literature published between January 2010 and May 2024.

Interventions to improve patient health education competence among nursing personnel: a scoping review protocol.

Introduction: Patient health education has gradually become an indispensable and important part of nursing work. However, nursing personnel's performance in this domain remains below satisfactory levels. The absence of patient health education competence (PHEC) constitutes a significant impediment to the effective implementation of such education by nursing personnel.

Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.

Objective: Long-term inhalation of silica dust particles leads to lung tissue fibrosis, resulting in impaired gas exchange and increased mortality. Silica inhalation triggers the aging of epithelial cells (AECs), which is a key contributor to the development of pulmonary fibrosis. Myricetin, a flavonoid compound extracted from Myrica genus plants, possesses various biological activities, including antioxidant and immunomodulatory effects.

Rice Reference Genes (RRG): redefining reference genes in rice by mining RNA-seq datasets.

Reverse transcription quantitative real-time PCR (RT-qPCR) is esteemed for its precision and reliability, positioning it as the standard for evaluating gene expression. Selecting suitable reference genes is crucial for acquiring accurate data on target gene expression. However, identifying appropriate reference genes for specific rice tissues or growth conditions has been a challenge.

Developing physics-informed neural networks for model predictive control of periodic counter-current chromatography.

The applications of continuous manufacturing technology in biopharmaceuticals require advanced design, monitoring, and control due to its complexity. Traditional mechanistic models, which rely on numerical solutions, suffer from long computational times, making them unsuitable for the timely demands of continuous processes and digital twin applications in biomanufacturing. This issue significantly limits the capability for real-time optimization and control.

Heteroatom Engineering in Earth-Abundant Cobalt Electrocatalyst for Energy-Saving Hydrogen Evolution Coupling with Urea Oxidation.

The development of multifunctional electrocatalysts with high performance for electrocatalyzing urea oxidation-assisted water splitting is of great significance for energy-saving hydrogen production. In this work, we demonstrate a novel heteroatom engineering strategy for development of B-doped Co as a multifunctional electrocatalyst for the hydrogen evolution reaction (HER), oxygen evolution reaction (OER), and urea oxidation reaction (UOR). Density functional theory (DFT) results suggest that a B dopant can efficiently adjust the electron reconstruction of the exposure of Co sites nearby and facilitate electron transfer, resulting in an optimal d-band center along with a lower Gibbs free energy barrier.

Taraxerone inhibits M1 polarization and alleviates sepsis-induced acute lung injury by activating SIRT1.

Background: Acute lung injury (ALI) is the most lethal disease associated with sepsis, and there is a lack of effective drug treatment. As the major cells of sepsis-induced ALI, macrophages polarize toward the proinflammatory M1 phenotype and secrete multiple inflammatory cytokines to accelerate the disease process through nuclear factor kappa-B (NF-κB) and NLR family pyrin domain containing 3 (NLRP3) inflammasome signaling pathways. Taraxerone, the main component of the Chinese medicinal Sedum, possesses numerous biological activities.

Nursing doctoral students' experiences of the courses and comprehensive examinations in China: a mixed-methods study.

Background: Understanding the experiences of doctoral students regarding courses and comprehensive examinations is crucial to enhance the quality of doctoral programs. Scarce information is available on the experiences of nursing doctoral students on the courses and comprehensive examinations in China. The purpose of this study was to understand the nursing doctoral students' experiences on courses and comprehensive examinations of the doctoral program at Xiangya School of Nursing, Central South University, and propose improvements.

Evaluation of the measurement properties of intimate partner violence screening instruments for the general population: A COSMIN-based international systematic review.

Aim: To systematically appraise, compare, and summarize the measurement properties of intimate partner violence screening instruments for the general population and provide recommendations.

Methods: We searched PubMed, Embase, Web of Science, ProQuest Dissertations & Theses Global and EBSCO Psychology Behavioral Sciences Collection from their establishment to March 2024 using systematic search strategies. The methodological quality of the instruments that met the inclusion criteria and their measurement properties were assessed using the COSMIN methodology, and the COSMIN recommendations were followed.

The effectiveness of yoga on menopausal symptoms: A systematic review and meta-analysis of randomized controlled trials.

Background: The highly prevalent menopausal symptoms among women, along with their deleterious health impacts, call for increased attention to the need for effective interventions targeting this growing public health problem. While increasing evidence demonstrates that yoga interventions benefit menopausal symptoms, no systematic review or meta-analysis has yet systematically examined the effectiveness of yoga on menopausal symptoms.

Objective: To systematically examine the effectiveness of Yoga in improving menopausal symptoms, hot flashes, depressive symptoms, anxiety, sleep quality, body mass index, systolic blood pressure, diastolic blood pressure, and quality of life among women with menopause.

A fine-grained image classification algorithm based on self-supervised learning and multi-feature fusion of blood cells.

Leukemia is a prevalent and widespread blood disease, and its early diagnosis is crucial for effective patient treatment. Diagnosing leukemia types heavily relies on pathologists' morphological examination of blood cell images. However, this process is tedious and time-consuming, and the diagnostic results are subjective, leading to potential misdiagnosis and underdiagnosis.

Interventions to improve illness-related communication between cancer patients and their minor children: A systematic review.

Background: Parental cancer conditions significantly impact the physical, social, and emotional well-being of minor children. Effective illness-related communication is crucial for both parents and their children to mitigate these effects.

Objective: To systematically summarize the characteristics and effectiveness of interventions aimed at improving illness-related communication between parents with cancer and their minor children.

An activatable near-infrared fluorescent probe with large Stokes shift for visualizing peroxynitrite in Alzheimer's disease models.

Alzheimer's disease (AD), characterized by its incurable nature and prevalence among the elderly, has remained a focal point in medical research. Increasing evidence suggests that peroxynitrite (ONOO) serves as a crucial biomarker for the diagnosis of AD. In this study, we present a novel, easily available, high-yield, and cost-effective near-infrared (NIR) fluorescent probe, CDCI-ONOO.

The relationship between arthritis and nocturia among adults under 60: A cross-sectional study based on National Health and Nutrition Examination Survey.

Objective: This study aims to investigate how arthritis, including osteoarthritis and rheumatoid arthritis, affects the incidence of nocturia in adults aged 20-59.

Methods: This study utilized data from the National Health and Nutrition Examination Survey from 2005 to 2020, involving 18 745 adults aged 20-59. Arthritis, including osteoarthritis and rheumatoid arthritis, was considered as the exposure factor, with nocturia as the outcome variable.

Photoinduced Co/Ni-cocatalyzed Markovnikov hydroarylation of unactivated olefins with aryl bromides.

Transition-metal-catalyzed hydroarylation of unactivated alkenes metal hydride hydrogen atom transfer (MHAT) is an attractive approach for the construction of C(sp)-C(sp) bonds. However, this kind of reaction focuses mainly on using reductive hydrosilane as a hydrogen donor. Here, a novel photoinduced Co/Ni-cocatalyzed Markovnikov hydroarylation of unactivated alkenes with aryl bromides using protons as a hydrogen source has been developed.

Multi-disease X-ray Image Classification of the Chest Based on Global and Local Fusion Adaptive Networks.

Background: Chest X-ray image classification for multiple diseases is an important research direction in the field of computer vision and medical image processing. It aims to utilize advanced image processing techniques and deep learning algorithms to automatically analyze and identify X-ray images, determining whether specific pathologies or structural abnormalities exist in the images.

Objective: We present the MMPDenseNet network designed specifically for chest multi-label disease classification.

The Circadian Rhythm of Itching among 241 Adults with Atopic Dermatitis: A Cross-sectional Study.

The pattern of itching in patients with atopic dermatitis has not been systematically studied. Therefore, this study aimed to assess the pattern of itching in adults with atopic dermatitis using questionnaires to assess for a circadian rhythm of itching in participating patients at a single institution (n = 241). A self-report questionnaire was used to assess circadian rhythm and intensity of itching in patients.

PGC1-Alpha/Sirt3 Signaling Pathway Mediates the Anti-Pulmonary Fibrosis Effect of Hirudin by Inhibiting Fibroblast Senescence.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic lung disease for which there is a lack of effective pharmacological treatments. Hirudin, a natural peptide extracted from leeches, has been used for broad pharmacological purposes. In this study, we investigated the therapeutic effects of hirudin on IPF and its related mechanism of action.

Prevalence and risk factors of depression among elderly people in nursing homes from 2012 to 2022: a systematic review and meta-analysis.

Objectives: To determine a pooled prevalence of depression and its influencing factors among nursing home residents.

Method: PsycINFO, PubMed, Embase, and Web of Science were searched for studies investigating the prevalence and risk factors of late-life depression among nursing home residents between January 2012 and November 2022. Two reviewers independently completed the literature screening, data extraction and quality assessment.

Psychometric validation of the Chinese versions of the quality of communication questionnaires for cancer patients and their family caregivers.

Background: Given the lack of valid and reliable instruments for evaluating the quality of communication between physicians and cancer patients and their family caregivers in China, this study translated and culturally adapted the Quality of Communication questionnaires for cancer patients (QOC-P) and their family caregivers (QOC-F) for use in the Chinese context and evaluated their psychometric properties.

Methods: The QOC-P and QOC-F were translated following an adapted version of Brislin's translation model and culturally adapted according to a Delphi expert panel. We pretested and refined the Chinese versions of the QOC-P and QOC-F among 16 dyads of patients and their family caregivers.