Synopsis of recent research by authors named "Si-jie Chen"
- Si-Jie Chen's recent research primarily focuses on developing innovative synthetic methodologies, particularly in the areas of selective hydroxylation of pyridines and C-H functionalization, which address challenges related to reactivity and regioselectivity in chemical transformations.
- His contributions include notable advances such as a photochemical method for C3 selective hydroxylation of pyridines and a general three-component alkyl Petasis boron-Mannich reaction, enhancing the accessibility of functionalized amines important for drug development.
- Additionally, Chen's research explores the mechanistic underpinnings of radical-relay reactions in copper-catalysis, providing insights into site-selectivity and expanding the synthetic possibilities to create diverse three-dimensional molecular structures.
