Publications by authors named "Si-hua Pan"
Background: Few studies have analyzed influenza B virus lineages based on hemagglutinin A (HA) gene sequences in southern China. The present study analyzed the HA gene and the lineages of influenza B virus isolates from Guangzhou during 2016, and compared our results with the WHO-recommended vaccine strain.
Methods: Ninety patients with influenza B were recruited from the First Hospital of Guangzhou Medical University.
Article Synopsis
- Researchers aimed to estimate the severity and prevalence of human infections caused by the influenza A(H7N9) virus in Guangzhou by analyzing stored blood samples from hospital patients between 2013 and 2014.
- The study tested 5,360 blood samples, resulting in the identification of only two positive cases, leading to an estimated total of 64,000 infections with a relatively low fatality risk of 3.6 deaths per 10,000 infections.
- The findings indicate that the actual incidence of A(H7N9) infections was much higher than previously reported laboratory-confirmed cases, highlighting the need for larger studies to better understand the virus's impact.
Background: Influenza A(H1N1)pdm09, A(H3N2) and B viruses have co-circulated in the human population since the swine-origin human H1N1 pandemic in 2009. While infections of these subtypes generally cause mild illnesses, lower respiratory tract infection (LRTI) occurs in a portion of children and required hospitalization. The aim of our study was to estimate the prevalence of these three subtypes and compare the clinical manifestations in hospitalized children with LRTI in Guangzhou, China during the post-pandemic period.
View Article and Find Full Text PDFBackground: The second wave of avian influenza H7N9 virus outbreak in humans spread to the Guangdong province of China by August of 2013 and this virus is now endemic in poultry in this region.
Methods: Five patients with H7N9 virus infection admitted to our hospital during August 2013 to February 2014 were intensively investigated. Viral load in the respiratory tract was determined by quantitative polymerase chain reaction (Q-PCR) and cytokine levels were measured by bead-based flow cytometery.
Article Synopsis
- The first confirmed case of the H7N9 virus in Guangdong Province, China, occurred in August 2013, outside the usual flu season, prompting an investigation into its source and transmission.
- A female patient with poultry exposure experienced severe respiratory symptoms and quickly moved to an ICU but ultimately recovered after four weeks, with no additional cases reported.
- Genetic analysis showed the virus shares similarities with other H7N9 strains and is susceptible to certain antiviral medications, highlighting a potential ongoing risk for H7N9 re-emergence in China, especially from environmental sources.
Objective: To investigate the clinical effect of Seinsheimer type V subtrochanteric femoral fractures with dynamic hip screw and shape memory alloy bow-teeth screw.
Methods: Twelve patients with Seinsheimer type V subtrochanteric femoral fractures were retrospectively analyzed. There were 8 males and 4 females with an average age of 53 years (range 31 to 65 years).
Objective: To explore a new method for the treatment of ankle joint fractures, and to evaluate its therapeutic effects.
Methods: Among 42 patients with ankle joint fractures, 34 patients had complete data for analysis, 19 patients were male and 15 patients were female, ranging in age from 21 to 61 years, with an average of 37 years. According to Weber-AO classification, there are 28 patients of B-type and 6 patients of C-type.