Publications by authors named "Si-Yu Song"
Background: Neuroticism has been associated with asthma, but the nature of this relationship remains unclear due to limited understanding of the impact of psychological factors on asthma risk. While Neuroticism is known to affect various health outcomes, its specific role in respiratory conditions like asthma is not fully understood.
Methods: We conducted Mendelian randomization (MR) analyses using genome-wide association studies (GWAS) to explore the causal link between 12 Neuroticism traits and asthma.
Objective: The aim of this study was to investigate the effects of soybean, medium-chain triacylglycerols (MCTs), olive oil, and fish oil (SMOF) on short-term clinical outcomes, physical growth, and extrauterine growth retardation (EUGR) in very preterm infants.
Methods: This was a multicenter retrospective cohort study of very preterm infants hospitalized in neonatal intensive care units at five tertiary hospitals in China between January 2021 and December 2021. According to the type of fat emulsion used in parenteral nutrition (PN), eligible very preterm infants were divided into the MCTs/long-chain triacylglycerol (MCT/LCT) group and SMOF group.
[Comparison of the impact of different fat emulsions on clinical outcomes in preterm infants with varying duration of parenteral nutrition: a randomized controlled multicenter study].
Zhongguo Dang Dai Er Ke Za Zhi
September 2023
Article Synopsis
- The study aims to assess how two different fat emulsions affect clinical outcomes in preterm infants on varying lengths of parenteral nutrition (PN).
- Preterm infants were split into two groups receiving either medium/long-chain triglyceride fat emulsion (MCT/LCT) or multi-oil fat emulsion (SMOF), and comparisons were made on clinical characteristics and outcomes.
- Results indicated that the SMOF group experienced lower triglyceride levels and significantly reduced risks of nutrition-related complications like cholestasis and bronchopulmonary dysplasia with longer PN durations, suggesting that SMOF is a better option for long-term use in preterm infants.
Background: It is proposed that the development of parenteral nutrition-associated cholestasis (PNAC) was significantly associated with preterm birth, low birth weight, infection, etc.; however, the etiology and pathogenesis of PNAC are not fully understood. Most of the studies examining PNAC-associated risk factors were single-center studies with relatively small sample sizes.
View Article and Find Full Text PDFObjective: This study compared the clinical effects of two different lipid emulsions in premature infants with gestational age < 32 weeks (VPI) or birth weight < 1500 g (VLBWI) to provide an evidence-based medicine basis for optimizing intravenous lipid emulsion.
Methods: This was a prospective multicenter randomized controlled study. A total of 465 VPIs or VLBWIs, admitted to the neonatal intensive care unit of five tertiary hospitals in China from March 1, 2021 to December 31, 2021, were recruited.