Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis.

Intraperitoneal dissemination is the main method of epithelial ovarian cancer (EOC) metastasis, which is related to poor prognosis and a high recurrence rate. Circular RNAs (circRNAs) are a novel class of endogenous RNAs with covalently closed loop structures that are implicated in the regulation of tumor development. In this study, hsa_circ_0001546 is downregulated in EOC primary and metastatic tissues vs.

The systemic immune-inflammation index is significantly associated with the severity of silicosis: a 9-year retrospective study in Beijing.

Background: Silicosis shows an increasing trend with the development of new industries. However, the potential biomarkers for predicting the disease severity are lacking. A novel inflammatory marker, the systemic immune-inflammation Index (SII), has not been studied in silicosis.

Recurrence and survival of patients with stage III endometrial cancer after radical surgery followed by adjuvant chemo- or chemoradiotherapy: a systematic review and meta-analysis.

Objective: To compare recurrence and survival in patients with stage III endometrial cancer after radical surgery, followed by either adjuvant chemoradiotherapy (ACR) or adjuvant chemotherapy (AC).

Methods: We searched for relevant studies in PubMed Central, Embase and the Cochrane Central Register of Controlled Trials. Data were pooled on rates of recurrence as well as rates of progression-free, disease-free and overall survival.

[Effectivity of Multiphase Fenton-like System of Iron Reduction Induced by Bisphenol A Authigenic Photoelectron].

In recent years, the Fenton-like (Fe-PMS/PS) advanced oxidation technology of persulfate activated by ferrous ions has been increasingly developed, but the difficulty of Fe reduction, which stops the reaction, still restricts its large-scale application. In this study, it was found that when some organic compounds represented by bisphenol A (BPA) were mixed with Fe and pristine TiO, some surface structures could broaden the light response range of TiO, capture visible light, and transfer the photoelectrons to Fe through TiO for reduction, so as to achieve an infinite cycle of Fe/Fe. According to the above principle, a BPA-TiO-Fe-PS composite system under visible light was constructed to degrade BPA, and its catalytic performance, catalytic mechanism, and influencing factors were discussed.

[Effect of Anaerobic Plug-flow on Nitrification Denitrifying Phosphorus Removal Aerobic Granular Sludge with Intermittent Aeration].

Actual domestic sewage has a complex composition and relatively low carbon and nitrogen content. Anaerobic plug-flow influent can enhance the utilization of COD by aerobic granular sludge by providing a locally high concentration of substrate. In this study, intermittent aeration was used to cultivate aerobic granular sludge in a sequencing batch reactor (SBR), and actual domestic sewage was used as the feed water to inoculate the sewage plant sludge.

[Temporal Anaerobic Effect on Aerobic Granular Sludge with Intermittent Influent-Intermittent Aeration].

To initiate the domestic sewage aerobic granular sludge (AGS) process, the experiment is operated by intermittent influent-effluent aeration to reduce the concentration of nitrate and the inhibition of PAO, and realize granulation by phosphate precipitation and positive electricity particles generated during phosphorus removal. The sludge from a sewage treatment plant is inoculated into the SBR reactors R1, R2, R3, and R4, for durations of 30, 60, 90, and 120 min total anaerobic time. This was used to study the effect of anaerobic time on the aerobic granular sludge system in domestic sewage.

[Aerobic Granular Sludge System with Multiple Influent-Aeration Operation Strategy].

SBR reactors R1 and R2 were used to inoculate activated sludge from a sewage treatment plant, and domestic sewage was used as the influent. The operation was carried out using a single and multiple influent-aeration operation strategy, respectively, and the particle size change and removal effect during the operation was studied. The results show that R1 and R2 successfully achieved sludge granulation after 56 days and 39 days of operation, respectively.

Progress in active compounds effective on ulcerative colitis from Chinese medicines.

Ulcerative colitis (UC), a chronic inflammatory disease affecting the colon, has a rising incidence worldwide. The known pathogenesis is multifactorial and involves genetic predisposition, epithelial barrier defects, dysregulated immune responses, and environmental factors. Nowadays, the drugs for UC include 5-aminosalicylic acid, steroids, and immunosuppressants.