Publications by authors named "Si-Young Park"

Background: Acupuncture and epidural steroid injection (ESI) are frequently performed in patients with degenerative lumbar disease. The purpose of this study was to explore preoperative acupuncture and ESI as risk factors for postoperative infection after elective lumbar fusion.

Methods: Patients >50 years of age who underwent spinal fusion due to degenerative lumbar disease from 2010 to 2019 were identified by diagnostic and procedural codes using a nationwide database.

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Biportal endoscopic spine surgery (BESS) is an emerging technique for lumbar spinal stenosis. Previous BESS techniques involve partial osteotomy for access to spinal canal such as partial laminotomy, partial facetectomy, and other forms to access the spinal canal for decompression. However, approaches that include osteotomy can cause bone bleeding intraoperatively, leading to obscured vision, and may be at risk of postoperative facet arthritis and segmental instability due to damage to the posterior stability structure.

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Background: Interest in the correlation between the spinopelvic complex and its radiographic parameters in early total hip arthroplasty has been increasing. This study investigated whether radiological spinopelvic parameters are risk factors for early total hip replacement (THR) within 1 year of spinal fusion surgery. The primary research question focused on identifying specific spinopelvic changes that may lead to early THR.

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  • * It involved stretching the fifth and sixth nerve roots using varying weights on cadavers, revealing that significant stretching occurred, particularly at higher weights, with average elongations of 1.94 mm at 8 kg and 5.03 mm at 20 kg.
  • * The findings suggest that shoulder traction may be a risk factor for PC5P, especially in patients with foraminal and central stenosis, highlighting the importance of informing patients about these risks prior to surgery.
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  • This study analyzed data from 188,581 patients who had lumbar spinal fusion from 2013 to 2018 to understand blood transfusion rates and associated risks.
  • It found that the rate of blood transfusions decreased significantly over the study period, from 56.38% to 47.51%, with comorbidities and surgical approach influencing the likelihood of receiving a transfusion.
  • The research also revealed that receiving a blood transfusion was linked to a higher risk of postoperative infections, highlighting the need for spine surgeons to evaluate patient risk factors carefully.
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Objective: In this study, we aimed to investigate whether multi-segment fusion or fusion-to-sacrum increases sacroiliac joint (SIJ) pathology compared with single-segment fusion or a non-fused sacrum.

Methods: This study included 116 patients who underwent lumbar or lumbosacral fusion and were followed up for 2 years. The patients were classified into single-segment fusion (n = 46) and multi-segment fusion (more than two levels, n = 70) groups and then reclassified into the non-fused sacrum (n = 68) and fusion-to-sacrum groups (n = 48).

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  • Early fusion is essential in spinal surgeries, particularly for patients with osteoporosis, to avoid complications from delayed healing, highlighting the importance of bone morphogenetic proteins (BMPs) in these procedures.
  • This study assesses the difference in time-to-fusion after single-level TLIF surgery in patients using recombinant human BMP-2 compared to those who do not, categorized by their bone density.
  • Results showed that patients receiving BMP-2 achieved fusion significantly faster (median of 2.5 years) compared to those not receiving it (median of 4 years), indicating the effectiveness of BMP-2 in improving fusion times.
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  • The study investigates the impact of untreated pre-surgical depression on post-surgical pain and recovery in patients undergoing spinal surgery.
  • Researchers evaluated 100 patients, assessing various depression and functional outcome scores before and after surgery.
  • The findings suggest that untreated depression may lead to worse functional outcomes and increased postoperative pain, highlighting the importance of pre-surgical depression screening and treatment for better recovery.
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Background: Recently, enhanced recovery after surgery (ERAS) protocols have attracted attention; they emphasize on avoiding intraoperative hypothermia while performing lumbar fusion surgery. However, none of the studies have reported the protocol for determining the temperature of saline irrigation during biportal endoscopic spine surgery (BESS) procedure. This study evaluated the effectiveness of warm saline irrigation during BESS in acute postoperative pain and inflammatory reactions.

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  • Understanding plant metabolites across the plant kingdom is challenging due to their vast diversity.
  • Researchers created the plantMASST reference database with data from 19,075 plant extracts, covering 246 botanical families, 1,469 genera, and 2,793 species.
  • This database enhances research on plant molecules, supporting drug discovery, biosynthesis, taxonomy, and ecology related to herbivore interactions.*
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Study Design: Retrospective cohort study.

Objective: To compare the incidence of adjacent segmental pathology (ASP) following minimally invasive (MI) vs open transforaminal lumbar interbody fusion (TLIF) and to identify factors linked to ASP requiring reoperation.

Methods: This retrospective study reviewed the outcomes of patients who underwent MI-TLIF or open TLIF.

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Background: Falls after orthopaedic surgery can cause serious injuries, which lengthen hospital stays and increase medical expenses. This has prompted hospitals to implement various fall-prevention protocols. The aims of this study were to determine the incidence of in-hospital falls after spine surgery, to analyze the overall risk factors, to discern factors that have a major influence on falls, and to evaluate the effectiveness of the fall-prevention protocol that we implemented.

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Study Design: Retrospective observational study.

Objective: To determine the proximity between screw and endplate of the upper instrumented vertebra (UIV) using a cortical bone trajectory (CBT) screw as a predictive factor for radiographic adjacent segment degeneration (ASD) in patients surgically treated with transforaminal lumbar interbody fusion (TLIF) with CBT screws (CBT-TLIF) with lumbar spinal stenosis.

Summary Of Background Data: The risk factors for radiographic ASD after CBT-TLIF remain unknown.

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Numerous adolescents diagnosed with adolescent idiopathic scoliosis (AIS) often manifest symptoms indicative of functional gastrointestinal disorders (FGIDs). However, the precise connection between FGIDs and AIS remains unclear. The study involved adolescents drawn from sample datasets provided by the Korean Health Insurance Review and Assessment Service spanning from 2012 to 2016, with a median dataset size of 1,446,632 patients.

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This retrospective study was designed to investigate the effectiveness of using a toothbrush, which is commonly used in our daily life, for biofilm removal and infection control in the treatment of spinal infections occurring after spinal fusion surgery. Currently, a biofilm is thought to form on the surface of the metal inserted during spine fusion surgery. We aim to determine the differences in clinical outcomes between using and not using a toothbrush to remove biofilm while performing conventional drainage, curettage, and debridement.

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As the area and range of surgical treatments in the orthopedic field have expanded, the development of biomaterials used for these treatments has also advanced. Biomaterials have osteobiologic properties, including osteogenicity, osteoconduction, and osteoinduction. Natural polymers, synthetic polymers, ceramics, and allograft-based substitutes can all be classified as biomaterials.

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The clinical and radiological results before and after surgery were compared and analyzed for patients with multilevel lumbar stenosis who underwent bi-portal endoscopic spine surgery (BESS) and microscopic unilateral laminotomy for bilateral decompression (ULBD). We retrospectively identified 47 and 49 patients who underwent BESS and microscopic ULBD, respectively, who were diagnosed with multi-level lumbar stenosis. Clinical outcomes were evaluated using the visual analog scale score for both back and leg pain, and medication (pregabalin) use and Oswestry Disability Index (ODI) scores for overall treatment outcomes were used pre-operatively and at the final follow-up.

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Study Design: A retrospective observational study.

Objective: This study investigated the clinical and radiological results of using cortical bone trajectory (CBT) screws versus traditional pedicle (TP) screws in transforaminal lumbar interbody fusion (TLIF) during a five-year follow-up of patients with single-level lumbar degenerative spondylolisthesis.

Summary Of Background Data: Few studies have compared five-year follow-up outcomes between CBT screws and TP screws in TLIF.

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Background: Malnutrition is prevalent among hospitalized older patients. Therefore, this study aimed to investigate the association between nutritional status [assessed using the Mini Nutritional Assessment (MNA) and serum albumin levels] and adverse outcomes in hospitalized older patients. We also aimed to compare the predictive utility of our findings.

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Patients with lumbar spinal stenosis (LSS) may experience neuropathic symptoms, such as back pain, radiating pain, and neurogenic claudication. Although the long-term outcomes of both nonsurgical and surgical treatments are similar, surgery may provide shortterm benefits, including improved symptoms and lower risk of falling. Decompression is mainly used for surgical treatment, and depending on the decompression degree and associated instability, combination therapy may be given.

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Background: Denosumab (DEN) and zoledronic acid (ZOL) currently represent the most potent antiresorptive agents for the treatment of osteoporosis. Despite similar effects on bone resorption, these agents have distinct mechanisms of action. The objective of this study was to compare the effect of DEN and ZOL after two-year administration on bone mineral density (BMD), trabecular bone score (TBS), bone turnover markers, and persistence.

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Background: Biportal endoscopic surgery has recently been performed in lumbar discectomy, with advantages over conventional surgery, such as less skin scarring and muscle damage. However, the clinical results have not been established. Although previous studies reported no difference between the biportal endoscopic and microscopic discectomy clinical results, the evidence was weak.

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Article Synopsis
  • Recent studies show positive outcomes for biportal endoscopic spine surgery but have small sample sizes and retrospective designs, prompting a more rigorous multicenter trial to compare it with conventional surgery.
  • This prospective, randomized controlled trial will enroll 120 patients with lumbar spinal stenosis from six hospitals and assess various outcomes over a 12-month period, including disability and pain levels.
  • The study aims to determine if biportal endoscopic surgery is as effective and safe as traditional methods, potentially influencing future clinical practice guidelines.
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Aims: Open discectomy (OD) is the standard operation for lumbar disc herniation (LDH). Percutaneous endoscopic lumbar discectomy (PELD), however, has shown similar outcomes to OD and there is increasing interest in this procedure. However despite improved surgical techniques and instrumentation, reoperation and infection rates continue and are reported to be between 6% and 24% and 0.

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