Publications by authors named "Si-Ying He"
Osteomyelitis (OM), characterized by heterogeneity and complexity in treatment, has a high risk of infection recurrence which may cause limb disability. Management of chronic inactive osteomyelitis (CIOM) without typical inflammatory symptoms is a great challenge for orthopedic surgeons. On the basis of data analysis of 1091 OM cases, we reported that latent osteogenic decline in CIOM patients was the main cause of secondary surgery.
View Article and Find Full Text PDFCurrently, fracture-related infection (FRI) still represents great challenges in front of orthopaedic surgeons, despite great advances that have been achieved regarding its diagnosis and treatment. Although both FRI and prosthetic joint infection (PJI) belong to osteoarticular infections and share similarities, FRI displays unique characteristics. Diagnosis of FRI is sometimes difficult owing to the nonspecific symptoms, and treatment is usually tricky, with a high risk of infection recurrence.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effectiveness of implant surface culture (ISC) alongside standard tissue sampling culture (TSC) for identifying bacteria responsible for fracture-device-related infections (FDRI).
- Between November 2020 and March 2022, patients needing implant removal were tested using both methods, revealing that ISC identified additional pathogens not detected by TSC.
- The results indicated that ISC not only had a higher positive detection rate but also yielded faster results compared to TSC, suggesting it could be a valuable tool in diagnosing FDRI.
Previous studies had reported that () gene polymorphisms were related to the development of several inflammatory disorders. However, potential links between such variations and the risk of developing a bone infection and underlying mechanisms remain unclear. This study aimed to analyze potential associations between genetic variations and susceptibility to extremity osteomyelitis (OM) in a Chinese Han population and investigate potential mechanisms.
View Article and Find Full Text PDFVariations in the vitamin D receptor () gene are related to several inflammatory disorders. However, the potential links between such alternations and the risk of developing late fracture-related infection (FRI) remain unclear. This study investigated associations between genetic variations in the and susceptibility to late FRI in the Chinese Han population.
View Article and Find Full Text PDFPurpose: This study investigated the incidence and risk factors of preoperative deep venous thrombosis (DVT) after an acute hip fracture.
Methods: We searched the electronic medical record system at our hospital for patients who received treatment for femoral neck (FN), intertrochanteric (IT), or subtrochanteric (ST) fractures between January 1, 2016, and December 31, 2020. DVT was diagnosed using venous compression ultrasonography.