Publications by Si-Yi Tong

Publications by authors named "Si-Yi Tong"

Eur J Pharm Sci

August 2023

Esculetin (ELT) is a well-known coumarin with strong antioxidant properties but has low solubility and absorption issues.
To enhance its solubility, researchers created a cocrystal of ELT using nicotinamide (NAM), which has good water solubility and can boost ELT's antioxidant effects.
The study found that this cocrystal significantly improved ELT's solubility and bioavailability, also showing enhanced antioxidant activity and potential liver protection in rat experiments.

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