Publications by authors named "Si-Yan Xing"

Background: Premature ejaculation (PE) is linked with abnormal brain activity that is modifiable by electroacupuncture (EA).

Aim: In this study we aimed to explore the central pathological mechanism underlying EA in treating PE.

Methods: Six-week-old male Sprague-Dawley rats were divided into a PE group (n = 8) and a control group (n = 8) according to ejaculatory frequency during copulatory behavior.

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Article Synopsis
  • - Peyronie's disease (PD) involves the formation of fibrous plaques in the penis, leading to curvature and other complications; this study tests four injectable agents to create a rat model for PD.
  • - TGF-β1 and fibrin injections caused pathology without curvature, while STS combined with TGF-β1 led to severe issues including necrosis and animal deaths.
  • - The combination of polidocanol (POL) with TGF-β1 produced similar pathological effects and curvature as STS + TGF-β1 but with fewer complications, suggesting it may be the safest and most relevant option for PD research.
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Recent research has highlighted structural and functional abnormalities in the cerebral cortex of patients with premature ejaculation (PE). These anomalies could play a pivotal role in the physiological mechanisms underlying PE. This study leveraged functional magnetic resonance imaging (fMRI), a noninvasive technique, to explore these neural mechanisms.

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